Evidence map›Paper›PMID 39929504›Full record

ArticleBMJ open2025

Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial.

Xue-Ying Liu, Mei-Rong Pan, Xue Gao, Zhong-Fang Fu, Lu Liu, Hai-Mei Li, Yu-Feng Wang, Qiujin Qian

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xue-Ying LiuInstitute of Mental Health, Peking University Sixth Hospital, Beijing, China.ORCID http://orcid.org/0009-0008-9976-783X
Mei-Rong Pan *Institute of Mental Health, Peking University Sixth Hospital, Beijing, China qianqiujin@bjmu.edu.cn panmeirong@bjmu.edu.cn.
Xue GaoInstitute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Zhong-Fang FuBeijing Key Laboratory of Behavior and Mental Health, Peking University School of Psychological and Cognitive Sciences, Beijing, China.
Lu LiuInstitute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Hai-Mei LiInstitute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Yu-Feng WangInstitute of Mental Health, Peking University Sixth Hospital, Beijing, China.
Qiujin Qian *Institute of Mental Health, Peking University Sixth Hospital, Beijing, China qianqiujin@bjmu.edu.cn panmeirong@bjmu.edu.cn.ORCID http://orcid.org/0000-0001-5060-3772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEmotional disorders are highly prevalent among adolescents, with a high rate of comorbidity. Convenient and effective treatment options are needed to reduce costs and improve effectiveness. The unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) is an evidence-based transdiagnostic approach aimed at ameliorate emotional symptoms. The objective of this study is to assess the efficacy of the UP-A in Chinese adolescents with emotional disorders using multidimensional evaluations. METHODS AND ANALYSIS: This study is a two-armed, randomised controlled trial on the efficacy of 12 week UP-A on adolescents with emotional disorders along with their parents. Forty-eight participants will be randomly assigned to either the treatment as usual (TAU) group or the TAU combined with UP-A (UP-A+TAU) group. We will evaluate the efficacy of the UP-A, through the following primary and secondary outcomes: emotional disorder severity, emotional symptoms, emotion regulation, cognitive patterns, executive function, resilience, quality of life, social and family functioning. Participants will be assessed at baseline (T1), week 4 (T2), week 8 (T3), post-treatment (T4) and 3 month follow-up (T5). DISCUSSION: This protocol outlines the first randomised controlled trial investigating the efficacy of the UP-A among Chinese adolescents with emotional disorders. The findings may contribute to providing an effective and feasible transdiagnostic intervention in Chinese clinical settings. ETHICS AND DISSEMINATION: This trial has been approved by the Ethics and Clinical Research Committees of Peking University Sixth Hospital and will be performed under the Declaration of Helsinki with the Medical Research Involving Human Subjects Act (WMO). The results will be disseminated in a peer-reviewed journal and a conference presentation. TRIAL REGISTRATION NUMBER: ChiCTR2300069354.

Indexed as

Affective SymptomsAdolescentChinaEmotional RegulationFemaleHumansMaleQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeAdolescentMENTAL HEALTHPSYCHIATRYRandomized Controlled Trial

Identifiers

PMID39929504
PMCPMC11815469

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.