Evidence map›Paper›PMID 39929255›Full record

ArticleJournal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research2025

Function of Interferon Lambda Receptor 1 Variants in Stem Cell-Derived Hepatocytes with Abrogated Endogenous

Laura A Novotny, Christiana S Kappler, Eric G Meissner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Mechanisms of Differential Signal Transduction by IFNLR1 Variants.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura A NovotnyDivision of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
Christiana S KapplerDepartment of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina, USA.
Eric G MeissnerDivision of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID 0000-0002-5240-7115

Funding

The role of SMAD1 and SATB2 in colon patterningP20GM130457 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Evan R Delgado · 2020 to 2026
$18.7M
NIGMS NIH HHS P20 GM130457
6 · The paper itself

Abstract

Distinct transcriptional isoforms of the interferon lambda receptor 1 (

Indexed as

Hepatitis C, ChronicHepatocytesReceptors, InterferonStem CellsHepacivirusHepatitis B virusHumansInterferonsProtein IsoformsVirus ReplicationIFNLR1 protein, humanInterferonsProtein IsoformsReceptors, Interferonhepatitis B virushepatocytesIFNLR1lambda interferonreceptor variants

Identifiers

PMID39929255
PMCPMC13588616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.