ArticleCaries research2025
Failures of Sealed Molars: Three-Year Results from a Multi-Centre, Prospective Study in Public Dental Service in Norway.
Article in Caries research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
introductionThe efficacy of fissure sealants (FS) in controlling occlusal caries is well documented. However, several factors can potentially modify the caries-preventive effect of FS and their failure rate in real life might be higher than in controlled experimental settings. The aim of this study was to prospectively examine failures and risk factors in sealed first permanent molars (FPMs) with sound occlusal surfaces or initial caries lesions of children in a practice-based setting in public dental service (PDS) in Norway.
methodsChildren aged 6-10 years considered at high caries risk (D
resultsOut of 409 participants, 4% (16) were lost to follow-up. Of 393 FPMs, 72% (284) were evaluated as success, 9% (34) as minor failure, and 19% (75) failed during the 36 months of this study period: 13% (51) received FS reapplication and 6% developed dentine caries or were restored. One third of FS were additionally treated with fluoride varnish (FV) at least once during the follow-up. Occlusal surface with caries grade 1-2 (vs. intact) increased (adjusted HR [adHR]: 1.9, 95% CI: 1.1-3.1), while FV application over FS decreased hazards (adHR 0.4, 95% CI: 0.3-0.7) for failure. The clinic's county was associated with failure.
conclusionAfter 3-year follow-up, nearly one out of five sealed FPMs failed, i.e., they had to be resealed, developed dentine caries, or were restored. Initial caries lesion on occlusal surface increased, while FV application over FS reduced risk for failure. Moreover, regional differences in sealed FPM failures were observed.
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