Evidence map›Paper›PMID 39929116›Full record

Trial reportJournal of anxiety disorders2025

Understanding emotion dysregulation in PTSD - GAD comorbidity.

Lucy J Allbaugh, Lucas Marinack, Alison M Pickover, Abigail Powers, Erica D Marshall Lee, Marylène Cloitre, Nadine J Kaslow

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of anxiety disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucy J AllbaughDepartment of Psychology, University of Dayton, Dayton, OH, United States. Electronic address: lallbaugh1@udayton.edu.
Lucas MarinackDepartment of Psychology, University of Wyoming, Laramie, WY, United States.
Alison M PickoverWave Life Inc., Menlo Park, CA, United States.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Erica D Marshall LeeDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Marylène CloitreNational Center for PTSD Dissemination and Training Division, Palo Alto VA Health Care System, Palo Alto, CA; NYU Silver School of Social Work, New York, NY, United States.
Nadine J KaslowDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.

Funding

Implementation of an Evidence-Based PTSD Treatment in Public Sector SettingsR01MH086611 · NIMH · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI CLOITRE, MARYLENE · 2011 to 2015
$4.6M
NIMH NIH HHS R01 MH086611
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) frequently co-occurs with myriad mood and anxiety disorders including generalized anxiety disorder (GAD). Despite this comorbidity's prevalence, mechanisms underlying the co-occurrence of PTSD and GAD remains understudied. An emotion dysregulation framework routinely is used to understand both PTSD and GAD but has not been applied to the PTSD-GAD comorbidity. Using MANOVA, the present study tested domains of emotion dysregulation (DERS) and of positive emotion regulation (AEQ) as differentiators of PTSD alone versus PTSD with GAD using pre-intervention data from a randomized controlled trial including 292 women with PTSD secondary to interpersonal violence. Five of six emotion dysregulation domains differentiated the two groups: fewer regulation strategies, nonacceptance of emotional responses, impulse control difficulties, lack of emotional awareness, and lack of emotional clarity were associated with comorbidity. Of three positive emotion regulation domains, participants with PTSD alone reported more positive emotionality than those with PTSD and GAD, and those with comorbid PTSD and GAD reported more negative affective interference than those with PTSD only. Rather than specific domains underlying unique presentations, findings indicate a general dysregulation factor, where PTSD-GAD comorbidity is supported by an overall higher level of emotion dysregulation as compared to PTSD alone.

Indexed as

Anxiety DisordersEmotional RegulationStress Disorders, Post-TraumaticAdultComorbidityFemaleHumansMiddle AgedEmotion dysregulationGeneralized anxiety disorderPosttraumatic stress disorder

Identifiers

PMID39929116
PMCPMC13248888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.