Evidence map›Paper›PMID 39928842›Full record

ArticleDevelopmental medicine and child neurology2025

Reproducibility of the Motor Optimality Score-Revised in infants with an increased risk of adverse neurodevelopmental outcomes.

Carly Luke, Arend F Bos, Michelle Jackman, Robert S Ware, Anya Gordon, Christine Finn, Dyvonne H Baptist, Katherine A Benfer, Margot Bosanquet, Roslyn N Boyd

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In one paragraph

Article in Developmental medicine and child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carly LukeQueensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-2732-1942
Arend F BosBeatrix Children's Hospital, Division of Neonatology, University of Groningen, Groningen, the Netherlands.ORCID 0000-0002-6103-6125
Michelle JackmanJohn Hunter Children's Hospital, Newcastle, Australia.ORCID 0000-0002-5467-1649
Robert S WareGriffith Biostatistics Unit, Griffith University, Brisbane, Australia.
Anya GordonDepartment of Physiotherapy, Townsville Hospital and Health Service District, Townsville, Australia.
Christine FinnQueensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, The University of Queensland, Brisbane, Australia.
Dyvonne H BaptistBeatrix Children's Hospital, Division of Neonatology, University of Groningen, Groningen, the Netherlands.
Katherine A BenferQueensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-7252-5063
Margot BosanquetDepartment of Health and Wellbeing, Townsville Hospital and Health Service District, Townsville, Australia.
Roslyn N BoydQueensland Cerebral Palsy and Rehabilitation Research Centre, Child Health Research Centre, The University of Queensland, Brisbane, Australia.ORCID 0000-0002-4919-5975

Funding

Cerebral Palsy Alliance Research Foundation PHD02619National Health and Medical Research Council Early Career Fellowship, APP1145212National Health and Medical Research Council Investigator grant, 1195602Perpetual IMPACT Philanthropy grant, IPAP2020/0808
6 · The paper itself

Abstract

aimTo determine reproducibility of the Motor Optimality Score-Revised (MOS-R) to assess infants at high risk of adverse neurodevelopmental outcomes, including cerebral palsy (CP), autism, and developmental delays.

methodThirty infants (18 males, 12 females, gestational age mean [range] = 32.5 [23-41] weeks) were randomly selected, according to 2-year outcome (typically developing; CP; or adverse neurodevelopmental outcome [ad-NDO]) from a prospective cohort. Participants had two General Movements videos between 12 weeks and 15 + 6 weeks corrected age. Six assessors, masked to history and outcomes, independently scored the MOS-R from videos. Assessors scored either one (Group 1; n = 3) or two videos for each infant (Group 2; n = 3). Intraclass correlation coefficient (ICC), Gwet's agreement coefficient, and limits of agreement were calculated.

resultsCombined interassessor reliability (IRR) over six assessors for total MOS-R was 'fair' (ICC = 0.56, 95% confidence interval [CI] 0.41-0.72), and 'excellent' with consensus agreement (ICC = 0.99, 95% CI 0.98-0.99). Analyses demonstrated a mean interrater difference of 0.316 (95% limits of agreement -11.51, 12.14) over 450 comparisons (15 pairs). IRR was 'moderate' to 'almost perfect' across subcategories, with the highest reliability 'movement patterns' (Gwet's agreement coefficient = 0.73-1.00) and the lowest 'postural patterns' (0.45-0.73). Assessors who scored two videos (Group 2) demonstrated higher reproducibility. IRR for total MOS-R was 'excellent' when infants were typically developing (ICC = 0.90), and 'good' for CP (0.74) and ad-NDO (0.68).

interpretationThe MOS-R is a highly reproducible tool for assessing infants at high risk of ad-NDOs and is feasible for implementation in clinical settings. Reproducibility is best when the tool is used by experienced assessors to gain consensus agreement.

Indexed as

Autistic DisorderCerebral PalsyDevelopmental DisabilitiesFemaleHumansInfantMaleProspective StudiesReproducibility of Results

Identifiers

PMID39928842
PMCPMC12336395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.