Evidence map›Paper›PMID 39928611›Full record

ArticlePloS one2025

Gaps, challenges and opportunities towards achieving the 95-95-95 targets in Cameroon: A systematic review and meta-analysis protocol.

Ezechiel Ngoufack Jagni Semengue, Alex Durand N K A, Pamela Patricia Tueguem, Christelle Aude Ka'e, Evariste Molimbou, Lum Yah Forgwei, Naomi-Karell Etame, Aurelie Minelle Kengni Ngueko, Désiré Takou, Aristide Stephane Abah Abah and 15 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Ezechiel Ngoufack Jagni SemengueChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.ORCID https://orcid.org/0000-0001-8768-2371
Alex Durand N K AChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Pamela Patricia TueguemChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Christelle Aude Ka'eChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Evariste MolimbouChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Lum Yah ForgweiChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Naomi-Karell EtameChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Aurelie Minelle Kengni NguekoChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Désiré TakouChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Aristide Stephane Abah AbahDepartment of Disease, Epidemics and Pandemic Control, Ministry of Public Health, Yaoundé, Cameroon.
Alice KetchadjiDepartment of Disease, Epidemics and Pandemic Control, Ministry of Public Health, Yaoundé, Cameroon.
Pamen BoubaDepartment of Financial resources and assets, Ministry of Public Health, Yaoundé, Cameroon.
David Kob SameJoint United Nations Programme on AIDS (UNAIDS), Country Office, Yaoundé, Cameroon.
Oscar EtogoWorld Health Organization, Country Office, Yaoundé, Cameroon.
Basile KeugoungUnited Nations Children's Fund (UNICEF), Country Office, Yaoundé, Cameroon.
Abdelkader BachaUnited Nations Children's Fund (UNICEF), Country Office, Yaoundé, Cameroon.
Phanuel HabimanaWorld Health Organization, Country Office, Yaoundé, Cameroon.
Martin Samuel SossoChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Alexis NdjoloChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Carlo-Federico PernoChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Vittorio ColizziChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.
Rogers AjehFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Anne-Cecile Z-K BissekFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
Nicaise NdembiAfrica Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-5131-3136
Joseph FokamChantal BIYA International Reference Centre for Research on HIV/AIDS Prevention and Management, Yaoundé, Cameroon.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundGiven HIV elimination by 2030, the World Health Organization and the United Nations' Programme on HIV/AIDS (UNAIDS) have set three programmatic goals that all countries should have achieved before 2025; 95% of people living with HIV should know their status (target-1); 95% of people who know their status should be linked to treatment (target-2); and 95% of people on treatment should achieve viral load suppression (i.e. VL<1000 copies/ml; target-3). Despite considerable global progress over the past decade, many low-middle-income countries are still below the expected targets. This review protocol aims to provide a standardized document for in-depth analysis of the strengths, weaknesses, opportunities and threats (SWOT) towards achieving these programmatic targets in Cameroon.

methodsThis systematic review will include randomized and non-randomized trials, cohorts, case-controls, cross-sectional studies, case reports and governmental notices addressing the achievements, the gaps, the challenges and the opportunities towards the 95-95-95 targets in Cameroon. The search will consider studies from 2017 to 2024, retrieved from PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, Google Scholar, online African journals, and Cumulative Index to Nursing and Allied Health Literature. We will include studies reporting HIV diagnosis, HIV link to treatment or HIV viral suppression in Cameroon. Results will be stratified according to time, age-group (adults' vs adolescents/children) and geographic locations. Primary outcomes will be "estimates on 95-95-95 programmatic goals at the national level". Secondary outcomes will consist of the SWOT analysis towards achieving these programmatic targets. A random-effects model will be used to calculate pooled prevalence if data permits.

conclusionsThis systematic review and meta-analysis protocol will guide global estimation on the achievement of the 95-95-95 targets as well as the stakes and challenges within the Cameroonian setting. Final evidence from the systematic review will allow identification of the gaps and measures to be taken to fasten our move towards the 95-95-95 in Cameroon by 2025. SYSTEMATIC REVIEW REGISTRATION: Systematic review registration: CRD42024502755.

Indexed as

HIV InfectionsCameroonHumansMeta-Analysis as TopicSystematic Reviews as TopicViral Load

Identifiers

PMID39928611
PMCPMC11809780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.