ArticlePloS one2025
Quantitative nylon monomerization by the combination of chemical pretreatment and enzymatic hydrolysis using nylon hydrolases.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Advances in amidases and urethanases as depolymerization biocatalysts.Nature chemical biology · 2026Review
- Reaction Optimization for Enzymatic Deconstruction of Industrially Relevant Nylon Composites.Chembiochem : a European journal of chemical biology · 2026Article
- Challenges and opportunities in the enzymatic recycling of nylons.Nature chemical biology · 2026Review
- Microbial and Enzymatic Degradation of Nylon: Mechanisms, Diversity, and Biotechnological Application.Journal of microbiology and biotechnology · 2026Review
- Circularity in Sequence-Controlled Copolyamides Enabled by Regioselective Enzymatic Hydrolysis.Journal of the American Chemical Society · 2026Article
- Iterative Synthesis and Marine-Biodegradation Assessment of Discrete Oligomers Based on Poly(Butylene Succinate), Poly(Ethylene Terephthalate), Polyamide 6, and Polyisoprene.Macromolecules · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nylons, derived from fossil fuels, are widely used for their toughness and flexibility, but they pose environmental concerns due to their low biodegradability. This study explored an efficient method for the monomerization of polymeric nylons, specifically nylon-6 and nylon-6,6, through a combination of chemical pretreatment and enzymatic hydrolysis using two kinds of nylon hydrolases, NylB and NylC (Nyl series enzymes). To break down the strong intermolecular hydrogen bonding between polymer chains of nylon, two pretreatment methods were investigated: homogeneous dispersion and soluble oligomerization induced by acid treatment. Homogeneous dispersion enhances water solubility, while soluble oligomerization reduces the molecular weight. These pretreatments significantly increased the enzyme sensitivity of the nylons, resulting in nearly complete conversion into monomers by Nyl series. Finally the convincing monomerization toward market products such as used fishing nets was also achieved. This study highlights the potential of this methodology for chemical recycling, offering a promising solution for reducing environmental impacts and achieving a circular economy for nylon products.
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