Evidence map›Paper›PMID 39928207›Full record

ArticleJournal of ophthalmic inflammation and infection2025

Retinitis linked to human herpesvirus type 6: a case study in a splenectomised patient.

Joana Santos-Oliveira, Ana Maria Cunha, Ana Filipa Moleiro, Margarida Ribeiro, Sónia Torres-Costa, Cláudia Oliveira-Ferreira, Ana Catarina Pedrosa, Joana Araújo, Luís Figueira, Marta Silva

Abstract read
In one paragraph

Article in Journal of ophthalmic inflammation and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joana Santos-OliveiraDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal. u016825@chsj.min-saude.pt.ORCID http://orcid.org/0000-0003-0260-8469
Ana Maria CunhaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0002-8519-8786
Ana Filipa MoleiroDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0003-3374-0016
Margarida RibeiroDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0002-0196-3840
Sónia Torres-CostaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0002-7079-9554
Cláudia Oliveira-FerreiraDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0002-9446-7140
Ana Catarina PedrosaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0001-6831-5488
Joana AraújoDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0002-6140-096X
Luís FigueiraDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0000-0002-4481-882X
Marta SilvaDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, 4200-319, Portugal.ORCID http://orcid.org/0009-0000-5906-6061

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human herpesvirus-6 (HHV-6) is a member of the HHV family and is a rare cause of infectious uveitis. We report a case of a splenectomised patient, hospitalised due to invasive pneumococcal disease, who was diagnosed with retinitis in the right eye, with good visual acuity (0.1 LogMAR). Given the presence of HHV-6 Polymerase chain reaction (PCR) in the cerebrospinal fluid and the serum and the coexistence of a severe central nervous system infection, the ophthalmological features were attributed to the HHV-6 infection. He was treated with topical corticosteroid eyedrops, cyclopentolate, and prednisolone acetate ointment and systemically with intravenous ganciclovir 5 mg/kg bid for 14 days and then oral valganciclovir 900 mg bid for 4 weeks. The diagnosis was promptly presumed, enabling the early initiation of appropriate treatment and contributing to the preservation of the good visual acuity initially observed.

Identifiers

PMID39928207
PMCPMC11811316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.