Evidence map›Paper›PMID 39928177›Full record

ArticleDiscover oncology2025

A bibliometric analysis of immune response in oral cancer.

Rongrong Zhang, Runying Guo, Yuqi Xin, Qingkun Jiang, Jiaxuan Qiu

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rongrong ZhangDepartment of Stomatology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Runying GuoDepartment of Stomatology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yuqi XinDepartment of Stomatology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Qingkun JiangDepartment of Stomatology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jiaxuan QiuDepartment of Stomatology, The First Affiliated Hospital of Nanchang University, Nanchang, China. xqiujiaxuan@163.com.

Funding

Jiangxi Natural Science Foundation 20232BAB216073, 20242BAB25514Key Projects of Jiangxi Administration of Traditional Chinese Medicine GZY-KJS-2023-028National Natural Science Foundation of China 82260194, 82403716
6 · The paper itself

Abstract

backgroundOral squamous cell carcinoma (OSCC), a type of oral cancer, has a high mortality rate and unfavorable outcomes. Its tumor microenvironment (TME) is intricate and adaptable, with research frequently focusing on the immune reaction. Scholars are exploring ways to enhance survival by bolstering the immune response within the TME. However, a comprehensive trend analysis is lacking. Bibliometric analysis can address this by visualizing research patterns. This study aimed to map these trends in OSCC immunology from 2003 to 2023.

methodsAn immunology-focused search on OSCC was executed within the Web of Science Core Collection, spanning 2003 to 2023. Despite its narrow focus, the search offers a telling glimpse of current researches in this domain. Bibliometric analysis was performed using VOSviewer, Citespace, Scimago Graphica, and R software.

resultsFrom 2003 to 2023, the field has published 805 publications, predominantly from China and the United States. The most valuable contributing author is Friedman Jay, topping co-citation counts. The journal Oral Oncology is the leading journal with the highest publication volume. An analysis of keyword bursts indicated that research into nivolumab and chemotherapy is a prevalent area of interest within the clinical community. These findings suggest that neoadjuvant immunotherapy represents a promising avenue for future therapeutic development.

conclusionsThis study presented a summary of the current trends and research frontiers in the field of immunological aspects of OSCC. This summary can serve as a valuable reference and a source of new insights into this area of research.

Indexed as

Bibliometric analysisChemotherapyNeoadjuvant immunotherapyNivolumabOral cancerOSCC (Oral squamous cell carcinoma)Tumor microenvironment

Identifiers

PMID39928177
PMCPMC11811321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.