Evidence map›Paper›PMID 39928144›Full record

ArticlePlanta2025

CERK1-mediated phosphorylation of PBL19 is crucial for antifungal defense in plants.

Yujia Li, Xiangjuan Huang, Ben-Qiang Gong, Yang Yu, Jian-Feng Li, Jiao Xue

Abstract read
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In one paragraph

Article in Planta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Fenaminosulf Promotes Growth and Gall Formation inPlants (Basel, Switzerland) · 2025
    Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yujia LiGuangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Science, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
Xiangjuan HuangGuangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Science, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
Ben-Qiang GongGuangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Science, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
Yang YuGuangdong Key Laboratory of Crop Germplasm Resources Preservation and Utilization, Agro-Biological Gene Research Center, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, People's Republic of China.
Jian-Feng LiGuangdong Provincial Key Laboratory of Plant Stress Biology, School of Life Science, Sun Yat-Sen University, Guangzhou, 510275, People's Republic of China.
Jiao XueGuangdong Key Laboratory of Crop Germplasm Resources Preservation and Utilization, Agro-Biological Gene Research Center, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, People's Republic of China. xuejiao@gdaas.cn.ORCID http://orcid.org/0009-0003-4385-142X

Funding

National Natural Science Foundation of China 32300454Natural Science Foundation of Guangdong Province 2023A1515012075the open subject of Guangdong Provincial Key Laboratory of Plant Stress Biology 2022PlantKF02
6 · The paper itself

Abstract

MAIN

conclusionPhosphorylation of PBL19 mediated by CERK1 in response to chitin is crucial for enhancing plant defense against fungal pathogens, underscoring the importance of chitin signaling in plant immune responses. Fungal pathogens pose a serious threat to global agriculture, causing substantial yield losses. Plants have evolved complex defense mechanisms, including the recognition of chitin, a major component of fungal cell walls, to activate immune responses that are crucial for defense against pathogens. Protein phosphorylation plays a pivotal role in regulating these responses, fine-tuning immune signaling pathways. Here, we investigate PBL19, a member of the RLCK VII subfamily in Arabidopsis thaliana, known for its pivotal role in chitin signaling pathways. Our study reveals that upon chitin perception, PBL19 undergoes phosphorylation-mediated by the receptor CERK1. Through mass spectrometry analysis, we identified eight specific phosphorylation sites on PBL19. Functional characterization revealed their crucial role in enhancing fungal resistance mechanisms in plants. This study advances our understanding of how plants employ phosphorylation-mediated signaling to combat fungal pathogens, providing insights into fundamental mechanisms of plant immunity.

Indexed as

ArabidopsisArabidopsis ProteinsPlant DiseasesPlant ImmunityProtein Serine-Threonine KinasesChitinDisease ResistancePhosphorylationSignal TransductionArabidopsis ProteinsCERK1 protein, ArabidopsisChitinProtein Serine-Threonine KinasesCERK1ChitinFungal resistancePBL19Phosphorylation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.