ArticleAnnals of medicine2025
Discrete truncation method for measuring the cardiac t2* values in patients with thalassemia.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveIn clinical work, it has been found that there are differences between the dark-blood (DB) and bright-blood (BB) cardiac magnetic resonance (CMR) T2* values (DB-T2* and BB-T2*) measured by the current automatic truncation method in patients with cardiac iron overload. The paper aims to develop a novel discrete truncation method to measure cardiac T2* value in patients with thalassemia.
methodsThe cardiac T2* values of 349 thalassemia (TM) patients (mean age, 13.41 years ±8.761, 173 males) from three hospitals during January 2011 to June 2023 were measured by CMRtools software. Different truncation methods were used to remove signal values that deviated from the fitting curve and the corresponding T2* values were recorded. The difference, correlation and consistency of DB-T2* and BB-T2* measured by different methods were compared.
resultsThere was no significant difference between DB-T2* and BB-T2* measured by discrete truncation method (DB-T2* vs.BB-T2*,
conclusionThe discrete truncation method is more stable and reliable than the automatic truncation method in the measurement of cardiac T2* value in TM patients.
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