Evidence map›Paper›PMID 39928115›Full record

ArticleAnnals of medicine2025

Rapid initiation of antiretrovirals at a syringe services program for people with HIV who inject drugs.

Marina Plesons, William Yang, Griffin M Sansbury, Edward Suarez, Chevel Collington, Elisha Ekowo, Katrina Ciraldo, Teresa Chueng, David P Serota, David W Forrest and 2 more

Abstract read
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marina PlesonsDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0003-3224-618X
William YangDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Griffin M SansburyDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0003-1558-7994
Edward SuarezDepartment of Psychiatry, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-5956-835X
Chevel CollingtonDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Elisha EkowoDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Katrina CiraldoDepartment of Obstetrics, Gynecology, and Reproductive Sciences, Department of Family Medicine and Community Health, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0003-2379-8062
Teresa ChuengDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
David P SerotaDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0001-8505-6617
David W ForrestDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
Tyler S BartholomewDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-9384-0812
Hansel E TookesDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0002-2369-360X

Funding

The Florida Node Alliance of the National Drug Abuse Treatment Clinical Trials NetworkUG1DA013720 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel J Feaster, Viviana Elizabeth Horigian · 2015 to 2026
$50.6M
Training Program on HIV and Substance Use in the Criminal Justice SystemT32DA037801 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Nabila El-Bassel, Lisa R Metsch · 2014 to 2026
$5.7M
NIDA NIH HHS T32 DA037801NIDA NIH HHS UG1 DA013720
6 · The paper itself

Abstract

backgroundPeople who inject drugs (PWID) living with HIV are less likely to receive care at early disease stages and have low rates of viral suppression. This study examined the feasibility and acceptability of rapid antiretroviral therapy (ART) initiation among PWID with HIV at a syringe services program (SSP) and assessed retention in care after transition to a traditional HIV clinic. PATIENTS/MATERIALS AND

methodsA mixed-methods single-arm pilot study was conducted at an SSP in Miami, Florida. Participants with HIV viral load >200 copies/mL were immediately connected with an HIV care provider and received HIV care and peer navigation at the SSP for 6 months, then were transitioned to a traditional HIV clinic. Demographic data were abstracted from the SSP's administrative records. Laboratory assessments and qualitative interviews were conducted at 1, 3, 6, 9, and 12 months.

resultsSixty-nine percent, 70%, and 69% of participants were virally suppressed (<200 copies/mL) at 1, 3, and 6 months, respectively. Following transition to a traditional HIV clinic, viral suppression remained high at 74% and 79% at 9 and 12 months, respectively. Themes were identified on: 1) barriers to care in traditional HIV clinics, 2) the SSP as a 'safe haven', 3) benefits of the rapid ART initiation program, 4) acceptability of telehealth, and 5) persistent barriers to engaging in HIV care.

conclusionRapid ART initiation for PWID at an SSP was acceptable and feasible and showed preliminary effectiveness in achieving HIV viral suppression and sustaining it after transition to a traditional HIV clinic.

Indexed as

Anti-HIV AgentsHIV InfectionsNeedle-Exchange ProgramsSubstance Abuse, IntravenousAdultFeasibility StudiesFemaleFloridaHumansMaleMiddle AgedPatient Acceptance of Health CarePilot ProjectsRetention in CareViral LoadAnti-HIV AgentsHIVinjection drug usesubstance usesyringe services programtelehealth

Identifiers

PMID39928115
PMCPMC11812110

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.