Evidence map›Paper›PMID 39928072›Full record

Trial reportAIDS and behavior2025

Individual and Contextual Determinants of ART Adherence Among a Sample of Young Black Gay, Bisexual, and Other Men Who Have Sex with Men Living with HIV in the United States.

Casey Morgan Luc, Kara Herrera, Sierra Upton, Jeb Jones, Meaghan Woody, Paul Burns, Li Liu, Antonio Jimenez, Mark S Dworkin

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Casey Morgan LucUniversity of Illinois Chicago, Chicago, IL, US. cluc2@uic.edu.ORCID http://orcid.org/0000-0003-3669-9821
Kara HerreraUniversity of Illinois Chicago, Chicago, IL, US.
Sierra UptonUniversity of Illinois Chicago, Chicago, IL, US.
Jeb JonesEmory University, Atlanta, GA, Georgia.
Meaghan WoodyEmory University, Atlanta, GA, Georgia.
Paul BurnsUniversity of Mississippi Medical Center, Jackson, MS, US.
Li LiuUniversity of Illinois Chicago, Chicago, IL, US.
Antonio JimenezUniversity of Illinois Chicago, Chicago, IL, US.
Mark S DworkinUniversity of Illinois Chicago, Chicago, IL, US.

Funding

A mobile phone intervention using a relational human talking Avatar to promote multiple stages of the HIV Care Continuum in African American MSMR01MH116721 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DWORKIN, MARK S · 2019 to 2023
$3.7M
NIH HHS R01MH116721
6 · The paper itself

Abstract

The Information-Motivation-Behavioral Skills (IMB) model of antiretroviral therapy (ART) adherence describes self-reported ART adherence determinants among people living with HIV (PLWH) who struggle to achieve optimal adherence, but less is known about young Black gay, bisexual, and other men who have sex with men (MSM), a group reported to have less than optimal ART adherence levels, partially affected by depression. Using the IMB model, we analyzed baseline data from 315 Black MSM living with HIV aged 18-34 years struggling with ART adherence enrolled in a multi-state mobile health (mHealth) randomized controlled trial. Generalized structural equation modeling was used to estimate the direct and indirect effects of (1) ART-related information, (2) motivation and (3) behavioral skills, or treatment self-efficacy, on non-optimal self-reported ART adherence (< 80%, Wilson's adherence measure). Prevalence of non-optimal ART adherence was 28.3%. Low behavioral skills were directly associated with non-optimal ART adherence (β = 0.69, SE = 0.10, p <.001). Low behavioral skills significantly mediated the relationship between low motivation and non-optimal ART adherence (Sobel z = 4.12, p <.001). Low information was not associated with treatment self-efficacy. Low motivation had a greater overall effect on non-optimal ART adherence among those with none/mild depressive symptomatology (β = 0.30, SE = 0.13, p <.001), and the direct effect of low motivation on non-optimal adherence was null among those with moderate/severe depressive symptomatology. Development of combination HIV prevention interventions designed to improve ART adherence should combine culturally appropriate mental health care into HIV treatment that go beyond social support among those who may be experiencing depressive symptomatology.

Indexed as

Anti-HIV AgentsBisexualityBlack or African AmericanHIV InfectionsHomosexuality, MaleMedication AdherenceSexual and Gender MinoritiesAdolescentAdultDepressionHumansMaleMotivationSelf EfficacyUnited StatesYoung AdultAnti-HIV AgentsAntiretroviral therapyBlack/African AmericanMen who have sex with menTreatment adherence

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.