Evidence map›Paper›PMID 39927781›Full record

ArticleAntimicrobial agents and chemotherapy2025

β-Lactamase diversity in

Andrew R Mack, Andrea M Hujer, Maria F Mojica, Magdalena A Taracila, Michael Feldgarden, Daniel H Haft, William Klimke, Arjun B Prasad, Robert A Bonomo

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. In vitro activity of aztreonam-avibactam against carbapenem-resistant Pseudomonas aeruginosa from Southern Brazil.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Mechanisms involved in cefiderocol resistance in FrenchAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Emergence of KPC-producingAntimicrobial agents and chemotherapy · 2026
    Article
  5. Article
  6. Identification of a novel gene inAntimicrobial agents and chemotherapy · 2026
    Article
  7. A Survey of the Microbiome, Culturome and ARG Profile of a Cohort of Chronic Diabetic Foot Lesions.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  8. Antimicrobial agents and chemotherapy · 2026
    Article
  9. Genomic and clinical characteristics ofMicrobiology spectrum · 2026
    Article
  10. Article
  11. Genomic Insights into Carbapenem-ResistantJournal of clinical medicine · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Antimicrobial Resistance Profiles ofPolish journal of microbiology · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Proteomic landscape of imipenem resistance inFrontiers in cellular and infection microbiology · 2025
    Article
  20. The Role ofInfection and drug resistance · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew R MackDepartment of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0002-0131-7996
Andrea M HujerResearch Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Maria F MojicaDepartment of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0002-1380-9824
Magdalena A TaracilaResearch Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Michael FeldgardenNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Daniel H HaftNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0001-8101-4938
William KlimkeNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Arjun B PrasadNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Robert A BonomoDepartment of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0002-3299-894X

Funding

Understanding ceftazidime resistance in SHV B-LactamasesR01AI063517 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI BONOMO, ROBERT A. · 2005 to 2023
$4.9M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) Michael FeldgardenHHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI063517HHS | NIH | U.S. National Library of Medicine (NLM) Michael FeldgardenNIAID NIH HHS R01 AI063517
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

beta-LactamasesPseudomonas aeruginosaAllelesAnti-Bacterial AgentsBacterial ProteinsDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsPseudomonas InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasesantibiotic resistancebeta-lactamasesbioinformaticsPseudomonas aeruginosa

Identifiers

PMID39927781
PMCPMC11881563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.