Evidence map›Paper›PMID 39927372›Full record

ArticleOpen veterinary journal2024

Effects of a blend extract of

Putri Reno Intan, Sukmayati Alegantina, Ani Isnawati, Nanang Yunarto, Fitrine Ekawasti, Ratih Rinendyaputri, Sunarno Sunarno, Yulvian Sani, Sela Septima Mariya, Ekowati Handharyani

Abstract read
In one paragraph

Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Putri Reno IntanAnimal Biomedical Study Program, IPB Postgraduate School, School of Veterinary Medicine and Biomedicine, IPB University, Bogor, Indonesia.
Sukmayati AlegantinaResearch Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center,-Bogor, Indonesia.
Ani IsnawatiResearch Center for Pharmaceutical Ingredients and Traditional Medicine, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center,-Bogor, Indonesia.
Nanang YunartoDepartment of Pharmacy, STIKES Widya Dharma Husada, South Tangerang, Indonesia.
Fitrine EkawastiResearch Centre for Veterinary Science, Research Organization for Health, National Research and Innovation Agency, Cibinong, Indonesia.
Ratih RinendyaputriCenter for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia.
Sunarno SunarnoCenter for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia.
Yulvian SaniResearch Centre for Veterinary Science, Research Organization for Health, National Research and Innovation Agency, Cibinong, Indonesia.
Sela Septima MariyaCenter for Biomedical Research, Research Organization for Health, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia.
Ekowati HandharyaniDivision of Pathology, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breastfeeding is vital for infant health, providing essential nutrients and protection against infections. Despite the benefits, many postpartum women face challenges in breastfeeding due to hypogalactia caused by stress, anxiety, or maternal illness. While medications, such as metoclopramide and domperidone, are sometimes prescribed to increase milk supply, they are limited due to safety concerns. As a result, there is a growing interest in alternative nonpharmacological interventions, including herbal galactagogues. Plants, such as Aim: This study aimed to investigate the influence of a combination of Methods: Twenty-four Sprague-Dawley rats were randomly divided into four groups at parturition. Each group, comprising six dams, was assigned a specific dose of 37.5, 75, and 150 mg/kg of the blended extract orally for 20 days postpartum, with one group serving as the control. Mammary glands were harvested and assayed for prolactin expression by immunohistochemistry. Results: The results showed that while the rate of milk production did not increase linearly with the duration of lactation, rats treated with the blended extract at a dose of 75 mg/kg exhibited higher milk production than the control group. Immunohistochemical analysis revealed increased prolactin expression in the mammary glands of rats treated with blend extract at 37.5 mg/kg ( Conclusion: The blended extract of

Indexed as

GalactogoguesLactationMoringa oleiferaPlant ExtractsSaururaceaeAnimalsFemaleMilkRatsRats, Sprague-DawleyGalactogoguesPlant ExtractsC. amboinicusImmunohistochemistryMammary glandsM. oleiferaS. androgynus

Identifiers

PMID39927372
PMCPMC11799640

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.