Evidence map›Paper›PMID 39927343›Full record

ReviewOpen veterinary journal2024

A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection.

Siti Rani Ayuti, Mirni Lamid, Sunaryo Hadi Warsito, Mohammad Anam Al-Arif, Widya Paramita Lokapirnasari, Zulfi Nur Amrina Rosyada, Sugito Sugito, Muslim Akmal, Rimayanti Rimayanti, Rakhi Gangil and 4 more

Abstract readReview
In one paragraph

Review in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Veterinary world · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Siti Rani AyutiDoctoral Program of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Mirni LamidDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Sunaryo Hadi WarsitoDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Mohammad Anam Al-ArifDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Widya Paramita LokapirnasariDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Zulfi Nur Amrina RosyadaDivision of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Sugito SugitoLaboratory of Veterinary Clinics and Surgery, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Muslim AkmalLaboratory of Histology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Rimayanti RimayantiDivision of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Rakhi GangilDepartment of Veterinary and Animal Husbandry Extension, College of Veterinary Science and AH MHOW, Nanaji Deshmukh Veterinary University, Jabalpur, India.
Aswin Rafif KhairullahResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Mutasem AbuzahraDoctoral Program of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Ikechukwu Benjamin MosesDepartment of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria.
Lili AnggrainiResearch Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Bogor, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myostatin (MSTN) is an essential gene that regulates muscle growth and development in livestock animals, influencing meat production and carcass quality. This review looks at MSTN genetic diversity in a variety of animals, including cattle, sheep, goats, and poultry, focusing on correlations between particular mutations and phenotypic parameters such as muscle mass and growth rate. Mutations in the MSTN gene have been linked to desirable features such as greater body weight and higher meat quality, making it an ideal candidate for genetic selection in breeding programs. Animals carrying this mutation frequently transform feed into muscle more efficiently, resulting in faster growth with less feed input. This is advantageous for growers seeking to cut feed costs while raising yields. MSTN-mutated animals convert feed into muscle more efficiently, lowering production costs over time and making them more appealing for commercial breeding operations. Advances in molecular genetics, especially CRISPR-Cas9 technology, have made it possible to precisely manipulate the MSTN gene, allowing for the development of calves with enhanced muscle mass. This article also examines the effects of MSTN variation on meat production efficiency, as well as current issues in animal genetics. This research synthesis emphasizes the significance of MSTN in cattle breeding, specifically its potential as a genetic marker to improve production and meat quality in commercial farming.

Indexed as

LivestockMeatMyostatinSelection, GeneticAnimalsBreedingCattleGoatsMutationSheepMyostatinGrowthMuscleMyostatinPoultryProductivity

Identifiers

PMID39927343
PMCPMC11799654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.