Evidence map›Paper›PMID 39927319›Full record

ArticleActa ortopedica brasileira2025

MICRO-FRAGMENTED ADIPOSE TISSUE IN THE KNEE OSTEOARTHRITIS UNDER LOCAL ANESTHESIA.

Bruno Butturi Varone, Henrique Fuller, Daniel Perini, Daniel Peixoto Leal, Riccardo Gomes Gobbi, Marco Kawamura Demange

Abstract read
In one paragraph

Article in Acta ortopedica brasileira, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bruno Butturi VaroneUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-3953-2712
Henrique FullerUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-8438-7059
Daniel PeriniUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0009-0005-1225-0028
Daniel Peixoto LealUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-8572-3210
Riccardo Gomes GobbiUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-1715-4343
Marco Kawamura DemangeUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-1999-9478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the feasibility of the entire micro fragmented adipose tissue knee injection procedure under local anesthesia. From the subcutaneous harvesting and microfragmentation process to the intrarticular knee injection. Methods: A patient with bilateral knee osteoarthritis underwent adipose tissue harvesting and bilateral intra-articular micro fragmented adipose tissue knee injection under local anesthesia. Patient-related outcomes were collected before the procedure, 12 months, and 24 months follow-up. Womac, Koos, and VAS were recorded. Results: The visual analog scale, KOOS questionnaire, and WOMAC score all improved in the 12- and 24-month follow-ups. Conclusion: Adipose tissue harvesting and micro fragmented adipose tissue knee injection are procedures that can be performed under local anesthesia and have good patient report outcomes.

Indexed as

Knee JointOsteoarthritis, KneeSubcutaneous Fat

Identifiers

PMID39927319
PMCPMC11801202

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.