Evidence map›Paper›PMID 39927227›Full record

ArticleClinical and experimental vaccine research2025

Discovery of novel vaccine candidates based on the immunogenic epitopes derived from

Seyyed Amir Hosseini, Saman Hashemi, Davood Siamian, Ali Asghari, Mohammad Fathollahzadeh, Hamidreza Majidiani, Iman Shahraki, Mohamad Hosein Safari

Abstract read
In one paragraph

Article in Clinical and experimental vaccine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Veterinary sciences · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seyyed Amir HosseiniDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.ORCID https://orcid.org/0009-0006-8993-0141
Saman HashemiMS.C. in Poultry Nutrition, College of Veterinary, Razi University, Kermanshah, Iran.ORCID https://orcid.org/0009-0007-4764-6908
Davood SiamianDepartment of Biology, Faculty of Basic Science, Islamic Azad University, Tonekabon Branch, Mazandaran, Iran.ORCID https://orcid.org/0009-0000-1682-0095
Ali AsghariSocial Determinants of Health Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID https://orcid.org/0000-0002-4005-2687
Mohammad FathollahzadehLiver and Gastrointestinal Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0009-0007-4752-0555
Hamidreza MajidianiHealthy Aging Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran.ORCID https://orcid.org/0000-0001-5568-1366
Iman ShahrakiFaculty of Veterinary Medicine, University of Zabol, Zabol, Iran.ORCID https://orcid.org/0009-0009-6621-1568
Mohamad Hosein SafariDepartment of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.ORCID https://orcid.org/0009-0004-9339-9264

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Due to the widespread distribution and importance of Materials and Methods: On this basis, 5 vaccine candidates were created using linkers ([GGGGS] Results: Polytopes with RS-09 alone (Toxo-App) and with IFN-γ (Toxo-Apfn), and one with 50S ribosomal protein (Toxo-Ribos) showed the highest immunogenicity during Conclusion: In conclusion, potent multi-epitope vaccine candidates were designed against toxoplasmosis using a diverse set of

Indexed as

ImmunoinformaticsToxoplasma gondiiVaccinationVaccine design

Identifiers

PMID39927227
PMCPMC11799584

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.