Evidence map›Paper›PMID 39927221›Full record

ArticleClinical and experimental vaccine research2025

A comparison between adjuvant and delivering functions of iron oxide and calcium phosphate nanoparticles, using a model protein against

Tahereh Goudarzi, Morteza Abkar, Mahdi Fasihi-Ramandi, Mohammadsaleh Peikar, Zahra Zamanzadeh

Abstract read
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In one paragraph

Article in Clinical and experimental vaccine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tahereh GoudarziDepartment of Genetics, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University, Isfahan, Iran.ORCID https://orcid.org/0000-0002-5223-2765
Morteza AbkarDepartment of Genetics, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University, Isfahan, Iran.ORCID https://orcid.org/0000-0002-8206-7035
Mahdi Fasihi-RamandiMolecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-3364-2638
Mohammadsaleh PeikarHematology/Oncology Division, Department of Internal Medicine, Isfahan University of Medical Science, Isfahan, Iran.ORCID https://orcid.org/0000-0002-5960-5982
Zahra ZamanzadehDepartment of Genetics, Faculty of Biological Sciences and Technology, Shahid Ashrafi Esfahani University, Isfahan, Iran.ORCID https://orcid.org/0000-0001-5967-4112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Calcium phosphate (CaP) and iron oxide (IO) nanoparticles (NPs) are promising adjuvants and delivery systems for vaccination. Furthermore, it has been shown that the chimeric antigen TF/Bp26/Omp31 (TBO) is a good candidate for stimulating protection against virulent Materials and Methods: The Results: Antibody levels showed that immunization with both CaP/TBO and IO/TBO NPs stimulated mixed Th1-Th2 immune responses. In addition, immunized mice were challenged with a virulent strain of Conclusion: Altogether, our results indicated that the CaP NPs are a potent adjuvant and delivery system for subcutaneously administered

Indexed as

BrucellosisCalcium phosphateIron oxideNanoparticles

Identifiers

PMID39927221
PMCPMC11799579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.