Evidence map›Paper›PMID 39927164›Full record

ArticleOpen medicine (Warsaw, Poland)2025

Lathyrol affects the expression of AR and PSA and inhibits the malignant behavior of RCC cells.

Shengyou Song, Lunwei Tai, Lei Zhou, Junling Jiang, Junfeng Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shengyou SongThe Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, 450002, China.
Lunwei TaiThe Second Clinical Medical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, 450002, China.
Lei ZhouDepartment of Urology, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, Henan 450002, China.
Junling JiangDepartment of Urology, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, Henan 450002, China.
Junfeng ZhaoDepartment of Urology, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, Henan 450002, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate how lathyrol affects aggressive behaviors and related proteins of the androgen receptor (AR) 786-O cells. Methods: 786-O cells were cultured Results: The negative control and experimental groups' cells exhibited reduced proliferation, migration, and invasion and increased apoptosis after 24 h treatment. Furthermore, these two group cells exhibited a notable reduction in the status of Ki67, Bcl-2, MMP2, MMP9, and p-Akt ( Conclusion:

Indexed as

androgen receptorlathyrolmalignant behavior of tumor cellsrenal cell cancer

Identifiers

PMID39927164
PMCPMC11806241

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.