Evidence map›Paper›PMID 39927140›Full record

ArticleHeliyon2025

Prediction model and scoring system for in-hospital mortality risk in infants with heart failure aged 1-36 months: A retrospective case-control study.

Meng Wei, Shuai Shang, Huasheng Lv, Xiaoyan Liang, Yanmei Lu, Baopeng Tang

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Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Meng WeiDepartment of Cardiac Function, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, Xinjiang, China.
Shuai ShangDepartment of Cardiac Function, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, Xinjiang, China.
Huasheng LvDepartment of Cardiac Function, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, Xinjiang, China.
Xiaoyan LiangDepartment of Cardiac Function, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, Xinjiang, China.
Yanmei LuDepartment of Cardiac Function, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, Xinjiang, China.
Baopeng TangDepartment of Cardiac Function, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830000, Xinjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Existing studies report very few factors influencing the mortality of infant and toddler heart failure patients during hospitalization. Due to its high mortality rate, it is an important health issue. Therefore, this study aims to explore the factors influencing infant and toddler heart failure patients during hospitalization, establish predictive models, and a mortality scoring table. Methods: The study ultimately included 544 cases of infant heart failure patients. They were randomly divided into a training set (380 cases) and a validation set (164 cases) in a ratio of 7:3. The training set was then further divided into the death group and the survival group for further analysis of indicators during hospitalization. Results: Using the Lasso regression method, this study selected the best 14 variables from 88 independent variables of infants and toddlers with heart failure. Multivariate Logistic regression results show that TP < 65 g/L (OR = 2.34), pH < 7.35 (OR = 2.79), and Respiratory rate (1-12 months: <30times/min and 13-36 months: <25times/min, OR = 2.34) are independent risk factors. The model evaluation results for the train and test sets of infant and toddler heart failure patients are as follows: C-index values for discrimination in the train and test sets are 0.721 and 0.728, respectively. Fit test calibration evaluations show P values of 0.9958 and 0.9998, both greater than 0.05, indicating good calibration. The AUC values for the train and test sets are 0.75 and 0.64, respectively, showing a good predictive effect of the model. The mortality scoring table divides patients in the train and test sets into low risk, moderate-risk, and high risk categories. Compared to the low risk group, the OR values for the occurrence of mortality in the Medium risk group and high risk group in the train set are 3.78 and 11.67, respectively; in the test set, the OR values for the moderate-risk group and high-risk group are 1.73 and 6.33, respectively. Conclusion: The predictive models and scoring tables established in this study have a good predictive role in assessing the risk of death in infant and toddler heart failure patients aged 1-36 months during hospitalization, providing clinical guidance and reference value.

Indexed as

DeathHeart failureInfants and young childrenPrediction modelScoring system

Identifiers

PMID39927140
PMCPMC11804692

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.