ArticleJournal of pharmacy & bioallied sciences2024
Estimation of Alpha-Amylase in Smokers with and without Leukoplakia and Oral Cancer-A Comparative Study.
Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Key Salivary Proteins Implicated in the Inhibition of Staphylococcus Aureus Biofilms by Chlorogenic Acid.European journal of dentistry · 2026Article
- Methodological Development of a Test for Salivary Proteome Analysis Useful in Lung Cancer Screening.International journal of molecular sciences · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
Background: Alpha-amylase is an enzyme found in saliva that plays a crucial role in the initial stages of digestion. Its levels can be influenced by various factors, including lifestyle habits such as smoking. Materials and Methods: A total of 150 male subjects were recruited for this comparative study and divided into three groups: 50 smokers without any oral lesions (group A), 50 smokers with leukoplakia (group B), and 50 smokers with oral cancer (group C). Salivary samples were collected from each participant and analyzed for alpha-amylase activity using the 2-chloro-4-nitrophenyl-β-D-maltotrioside (CNPG3) method. Data were statistically analyzed using ANOVA and post-hoc tests to compare the mean alpha-amylase levels between the groups. Results: The mean alpha-amylase levels were found to be 140 U/mL in group A, 180 U/mL in group B, and 220 U/mL in group C. Statistical analysis revealed a significant increase in alpha-amylase levels in smokers with leukoplakia and oral cancer compared to smokers without oral lesions ( Conclusion: The study demonstrates that salivary alpha-amylase levels are elevated in smokers with leukoplakia and oral cancer compared to those without these conditions.
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