ArticleJournal of pharmacy & bioallied sciences2024
Investigation of the Potential of Nanoparticles as a New Drug Delivery System for Endodontic Treatment.
Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Capped silver nanoparticle penetration in primary dentition: an in vitro SEM-EDS analysis.BMC oral health · 2026Article
- Bioactive Materials in Pediatric Endodontics: Current Applications and Future Directions.Cureus · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The application of nanoparticles in endodontic treatment presents a novel approach to drug delivery, potentially enhancing the efficacy of therapeutic agents. Materials and Methods: In this study, we synthesized and characterized nanoparticles of chitosan, calcium phosphate, and silver using standard protocols. The nanoparticles were then loaded with an antimicrobial agent, chlorhexidine, and incorporated into an endodontic sealer. The antibacterial efficacy of the nanoparticle-enhanced sealer was tested against Results: The synthesized nanoparticles exhibited a uniform size distribution, with an average diameter of 50 nm for chitosan, 30 nm for calcium phosphate, and 20 nm for silver nanoparticles. The antibacterial tests showed that the nanoparticle-loaded sealer achieved a 40% greater inhibition zone against Conclusion: Nanoparticles demonstrate significant potential as a drug delivery system in endodontic treatment, enhancing both the antibacterial efficacy and penetration depth of therapeutic agents.
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Registered trials
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