ArticleJournal of pharmacy & bioallied sciences2024
Investigating the Relationship Between Orthodontic Treatment and Temporomandibular Joint Disorders in Adolescents.
Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Adverse effects of removable orthodontic aligners: A systematic review with single-arm meta-analysis.PloS one · 2026Pooled it
- Research Hotspots and Emerging Trends of Orthodontic-Related Discomfort and Pain: A Bibliometric Review.Pain research & management · 2025Pooled it
- Article
- Impact of orthodontic treatment on temporomandibular joint function among adolescents: A longitudinal study.Bioinformation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Orthodontic treatment is widely utilized to correct malocclusions and improve dental aesthetics in adolescents. However, its potential association with the development of temporomandibular joint disorders (TMDs) remains controversial. Materials and Methods: A prospective cohort study was conducted involving 200 adolescents aged 12-18 years undergoing orthodontic treatment. Participants were divided into two groups: those receiving fixed appliances (n = 150) and those undergoing aligner therapy (n = 50). The presence and severity of TMDs were assessed using the Research Diagnostic Criteria for Temporomandibular Disorders at baseline, 6 months, and 12 months post-treatment initiation. Data were analyzed using the Chi-square tests and multivariate logistic regression to identify potential risk factors. Results: At baseline, 10% of the total cohort exhibited mild TMD symptoms. After 12 months, 25% of the fixed appliance group showed an increase in TMD symptoms, compared to 15% in the aligner group. The logistic regression analysis revealed a significant association between the duration of treatment with fixed appliances and the development of TMDs (OR = 2.5; 95% CI: 1.2-5.1; Conclusion: The findings suggest that prolonged orthodontic treatment with fixed appliances may increase the risk of developing TMDs in adolescents, whereas aligner therapy appears to have a minimal impact on TMJ function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.