Evidence map›Paper›PMID 39926781›Full record

ArticleJournal of pharmacy & bioallied sciences2024

Assessment of the Remineralizing Efficacy of Grape Seed Extract vs Sodium Fluoride on Surface and Subsurface Enamel Lesions: An

Deepak Sharma, Yogesh Sahu, Reema Srichand, Swapnali Mhatre, Uttam Shetty, Nikhil A Karhale, Sonu Acharya

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deepak SharmaDepartment of Conservative Dentistry and Endodontics, Bharati Vidyapeeth (Deemed to be) University Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Yogesh SahuDepartment of Conservative Dentistry and Endodontics, Maitri College of Dentistry and Research Center, Durg, Chhattisgarh, India.
Reema SrichandDepartment of Prosthodontics, Bharati Vidyapeeth (Deemed to be) University Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Swapnali MhatreDepartment of Prosthodontics, Bharati Vidyapeeth (Deemed to be) University Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Uttam ShettyDepartment of Prosthodontics, Bharati Vidyapeeth (Deemed to be) University Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Nikhil A KarhaleDepartment of Conservative Dentistry and Endodontics, Maitri College of Dentistry and Research Center, Durg, Chhattisgarh, India.
Sonu AcharyaPediatric and Preventive Dentistry, Institute of Dental Sciences, Sikhsha 'O' Anusandhan Deemed to be University, Bhubaneswar, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dental caries is a prevalent oral health issue, primarily resulting from demineralization of the enamel. Remineralizing agents such as sodium fluoride (NaF) have been widely used to counteract this process. Recent studies suggest that natural extracts, such as grape seed extract (GSE), may also have significant remineralizing properties. This study aims to compare the efficacy of GSE and NaF on surface and subsurface enamel lesions in an Materials and Methods: In this Results: The NaF group showed a significant increase in SMH (45%) and CSMH (35%) compared to the control group. The GSE group demonstrated a similar trend with a 40% increase in SMH and a 30% increase in CSMH. Both treatments were significantly more effective than the control ( Conclusion: Grape seed extract exhibits comparable remineralizing efficacy to sodium fluoride on both surface and subsurface enamel lesions

Indexed as

Dental cariesenamel remineralizationgrape seed extractin vitro studysodium fluoridesubsurface lesionssurface microhardness

Identifiers

PMID39926781
PMCPMC11805167

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.