ArticleJournal of pharmacy & bioallied sciences2024
Comparative Evaluation of Clinical and Radiographic Changes Following Delayed Implant Placement in Mandibular Posterior Region with or without i-PRF Activation: A Split Mouth Clinical Study.
Article in Journal of pharmacy & bioallied sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Response to the letter to the editor "Clinical and radiographic assessment of effect of platelet rich fibrin on dental implant osseointegration - A split mouth randomized clinical trial".Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Injectable platelet-rich fibrin (i-PRF) is prepared without anticoagulants having improved features such as increased fibroblast migration, proliferation, and tissue angiogenesis acceleration. When administered to titanium implants, i-PRF clings to the metal surface, generating a protein coating that impacts cellular activity required for osseointegration which aids in optimum and rapid osseointegration. The present study compared and evaluated the osteogenic properties of i-PRF in dental implant sites to determine the positive impact of i-PRF on osseointegration. Methods: A split-mouth clinical study design was used, involving ten participants with twenty sites of bilaterally missing mandibular molars. The subjects were divided into two equal treatment groups (N = 10): control group, where dental implants were placed without i-PRF activation, and test group, where i-PRF-activated dental implants were placed. Results: Both groups showed similar trends in plaque index and sulcular bleeding index. However, the test group exhibited significantly higher Implant Stability Quotient scores, indicating better stability. Peri-implant probing depth showed no significant difference between groups, but the test group had lower increase in probing depth. In addition, the test group showed superior wound healing and lower crestal bone loss changes compared to the control group. Conclusions: The findings of this study contributed to understand the effectiveness of i-PRF in enhancing osseointegration in dental implants, potentially improving clinical outcomes in implant dentistry.
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Registered trials
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