Evidence map›Paper›PMID 39926657›Full record

ArticlePakistan journal of medical sciences2025

The relationship between allergic diseases and neurodevelopmental disorders in children enrolled in primary healthcare.

Yusuf Adnan Guclu, Erdem Erkoyun, Selcuk Sinan Celik, Demet Can

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yusuf Adnan GucluYusuf Adnan Guclu, MD. Associate Professor, Department of Family Medicine, Izmir Faculty of Medicine, Health Sciences University, Tepecik Training and Research Hospital, Izmir, Turkiye.
Erdem ErkoyunErdem Erkoyun, MD. Specialist, Public Health Services Presidency, Provincial Health Directorate, Izmir, Turkiye.
Selcuk Sinan CelikSelcuk Sinan Celik, MD. Specialist Pediatric Clinic, Health Sciences University, Dr. Behçet Uz Children's Diseases, Surgery Training and Research Hospital, Izmir, Turkiye.
Demet CanDemet Can, MD. Professor, Department of Pediatric Immunology and Allergy Diseases, Izmir Faculty of Medicine, Health Sciences University, Dr. Behçet Uz Children's Diseases, Surgery Training and Research Hospital, Izmir, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: The prevalence of neurodevelopmental disorders (NDs) and allergic diseases(ADs) has increased in recent years. This study aimed to analyse the association between them among children registered at primary healthcare units in Izmir. Methods: For this retrospective cross-sectional study, primary healthcare units in Izmir were selected by randomisation conducted between January 1, 2023 and December 31, 2023. The dependent variables are attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). The risk factors are respiratory allergies and skin allergies. Logistic regression models were adjusted for age, sex, socioeconomic level. Results: There were 20,557 children registered in 26 primary healthcare units. Skin allergy was detected in 7.8%, respiratory allergy in 6.8%, ADHD in 1.2% and ASD in 0.0%. ADHD comorbidity was found to be high in both children with respiratory allergies and children with skin allergies (p<0.001). The rate of ASD comorbidity was 1.8% in boys with respiratory allergies and 1.6% in boys with skin allergies (p>0.01). The analysis could not be performed due to the low number of girls with ASD. The logistic regression models showed a higher odds ratio for respiratory allergies (OR:6.2, 95% CI: 4.6-8.3) than for skin allergies (OR:2.2, 95% CI: 1.5-3.2) for ADHD. Conclusion: It would be beneficial to increase awareness among healthcare providers and parents about the co-occurrence of NDs and ADs.

Indexed as

allergic rhinitisAsthmaAtopic dermatitisAttention deficit and hyperactivity disorderAutism spectrum disorderPrimary healthcare

Identifiers

PMID39926657
PMCPMC11803789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.