Evidence map›Paper›PMID 39926640›Full record

ArticleClinical case reports2025

A Case Report of Neuromyelitis Optica Spectrum Disorder (NMOSD) Treatment in Resource-Limited Setup: An Ethiopian Experience.

Sebhatleab T Mulate, Bereket A Molla, Berhanu M Abera, Tseganesh M Hailemariam, Yared Z Zewde

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebhatleab T MulateDepartment of Internal Medicine College of Health Science, Addis Ababa University Addis Ababa Ethiopia.ORCID https://orcid.org/0009-0006-0064-7236
Bereket A MollaDepartment of Internal Medicine College of Health Science, Addis Ababa University Addis Ababa Ethiopia.ORCID https://orcid.org/0000-0002-6267-6642
Berhanu M AberaDepartment of Internal Medicine College of Health Science, Addis Ababa University Addis Ababa Ethiopia.
Tseganesh M HailemariamCollege of Health Science, Addis Ababa University Addis Ababa Ethiopia.
Yared Z ZewdeDepartment of Neurology College of Health Science, Addis Ababa University Addis Ababa Ethiopia.ORCID https://orcid.org/0000-0002-6442-7148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MOSD is a rare and disabling immune-mediated inflammatory Astrocytopathic disease characterized by demyelination and axonal destruction, typically involving the spinal cord and the optic nerve. Here we present a case report of a 53-year-old female patient who had a pertinent history of treatment for optic neuritis a few months back, currently diagnosed with Neuromyelitis Optica after she presented with a three-week history of weakness of lower extremity, headache, and neuropathic pain. She was pulsed with methylprednisolone and started on azathioprine, which significantly improved her clinical condition. When patients with optic neuritis and transverse myelitis occur, a high index of suspicion for NMOSD is essential. Establishing a diagnosis based on clinical and MRI findings is crucial for initiating therapy quickly, halting more harm, and avoiding a delay in diagnosis. Our experience treating our patient shows that Azathioprine is still a practical choice in resource-limited setups.

Indexed as

AQP‐ 4azathioprineNMOSDoptic neuritistransverse myelitis

Identifiers

PMID39926640
PMCPMC11805675

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.