Evidence map›Paper›PMID 39926593›Full record

ArticleFrontiers in veterinary science2024

Genome-wide association studies with prolapsed gland of the third eyelid in dogs.

Yu Zeng, Cundong Feng, Zheli Jiang, Weian Du, Shan He, Xingnuan Li, Yi Fan, Xiao Ouyang, Bixin Huang, Yan Su and 6 more

Abstract read
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In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Yu Zeng *Jiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Cundong Feng *School of Tropical Agriculture and Forestry (School of Agricultural and Rural Affairs, School of Rural Revitalization), Hainan University, Haikou, China.
Zheli JiangJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Weian DuSchool of Stomatology and Medicine, Foshan University, Foshan, China.
Shan HeJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Xingnuan LiJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Yi FanJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Xiao OuyangJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Bixin HuangJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Yan SuJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Siyu WangJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Rongxing WeiNanchang Police Dog Base of the Ministry of Public Security of China, Nanchang, China.
Zonghao DaiNanchang Police Dog Base of the Ministry of Public Security of China, Nanchang, China.
Peng JinNanchang Police Dog Base of the Ministry of Public Security of China, Nanchang, China.
Jianyun LiuJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.
Qianyong YangJiujiang Key Laboratory of Rare Disease Research, Jiujiang University, Jiujiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cherry eye, the common name for the prolapse of the third eyelid gland in dogs, is a widespread ophthalmic disease affecting dogs of various breeds. This condition severely affects the quality of life of affected dogs, and its underlying cause remains unresolved. In this study, 170K SNP microarray data were collected from 653 brachycephalic dogs and 788 brachycephalic and mesocephalic dogs. These two datasets were analyzed separately in genome-wide association studies (GWAS) involving 12 dog breeds affected by cherry eye. The GWAS analysis of 653 short-headed dogs revealed that four SNPs in the CFA3:15627075-15983629 bp region exceeded the genome-level significance threshold. Association analysis of this region also indicated that these four SNPs were strongly associated. Gene annotation showed that the region contained genes such as

Indexed as

animal modelcaninecherry eyeeye diseasesgeneticsthird eyelid gland

Identifiers

PMID39926593
PMCPMC11804112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.