Evidence map›Paper›PMID 39926495›Full record

ArticleACS omega2025

Investigating the Role of Surface Confinement and Reaction Dynamics in the Production of Polyphenol-Based Nanoparticles.

Wei-Ting Chang, Ji-Young Lee, Leila F Deravi

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei-Ting ChangDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Ji-Young LeeDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.
Leila F DeraviDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.ORCID https://orcid.org/0000-0003-3226-2470

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of polyphenol-based particles as functional materials has demonstrated great promise for applications ranging from targeted therapeutics to environmental remediation due to their biocompatibility, potent reactivity, and modular chemistry. Despite these rich benefits, polyphenols remain difficult to formulate with due to their susceptibility to spontaneous aggregation in aqueous environments. In this study, we explore conditions that leverage this aggregation as a feature to seed the production of monodispersed (polydispersity index of <0.1) nanoparticles with controlled diameters <200 nm. To accomplish this goal, we evaluated the assembly dynamics of a heterogeneous population of green tea extracts in water and investigated the interplay between temperature, time, and surface confinement in both fixed vessels and emulsion droplets on particle size and uniformity. In both cases, homogeneous nanoparticles are created, highlighting a feasible pathway to control and scale the production of polyphenolic nanostructures for future materials applications.

Identifiers

PMID39926495
PMCPMC11799981

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.