ArticleSurgical neurology international2025
A rare case of brain metastatic malignant melanoma coexisting with black colored dura mater: Management in low-resource setting.
Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Brain metastases significantly contribute to morbidity and mortality in individuals with cancer, with melanoma exhibiting a high propensity for central nervous system dissemination. Early recognition and diagnosis are crucial, especially in low-resource settings where access to advanced diagnostics and treatment may be limited. Case Description: We present the case of a 63-year-old male with a history of metastatic melanoma who presented with progressive neurological deficits. Imaging revealed a solitary brain metastasis in the cerebellopontine angle, further complicated by diffuse melanotic infiltration of the dura mater. The patient underwent surgical resection of the cerebellopontine angle mass, and histopathological examination confirmed metastatic melanoma. Conclusion: This case highlights the importance of considering metastatic disease in the differential diagnosis of cancer patients presenting with neurological symptoms, even in atypical locations. The presence of dural melanosis underscores the aggressive nature of melanoma and the need for comprehensive evaluation. This case emphasizes the need for prompt diagnosis and management to optimize patient outcomes, particularly in resource-constrained environments.
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