Evidence map›Paper›PMID 39926394›Full record

ArticleFrontiers in endocrinology2024

Case report: Persistent syndrome of inappropriate antidiuresis after traumatic brain injury: spontaneous resolution and impact on RAAS and bone metabolism over five years.

Yaoxia Liu, Jiao Tang, Mingwei Zhou, Haotian Huang, Tao Wang, Min Zhang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yaoxia LiuDepartment of Geriatric Endocrinology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Jiao TangDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Mingwei ZhouSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Haotian HuangSchool of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Tao Wang *Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Min Zhang *Department of Geriatric Endocrinology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The syndrome of Inappropriate Antidiuresis (SIAD) is a well-known cause of hyponatremia and can be associated with various etiologies, including traumatic brain injury (TBI). Most cases of SIAD following TBI exhibit a pattern in which hyponatremia develops several days to weeks after the trauma and resolves within a few weeks. Here, we present a rare case of persistent SIAD caused by TBI that resolved spontaneously after five years. The patient experienced prolonged hyponatremia for several years and was ultimately diagnosed with post-traumatic SIAD after excluding other potential causes. Notably, the patient exhibited an unusual sensitivity to tolvaptan, accompanied by decreased renin levels and increased bone turnover markers. The condition resolved spontaneously after five years, with renin, aldosterone, and bone turnover markers returning to normal upon re-evaluation.

Indexed as

Bone and BonesBrain Injuries, TraumaticInappropriate ADH SyndromeRenin-Angiotensin SystemAdultHumansHyponatremiaMaleMiddle AgedRemission, Spontaneousbone metabolismhyponatremiarenin-angiotensin-aldosterone system (RAAS)SIADtolvaptantraumatic brain injury (TBI)

Identifiers

PMID39926394
PMCPMC11802408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.