ArticleFrontiers in endocrinology2024
Quantitative analysis of peripapillary RNFL capillary density and thickness in patients with mild nonproliferative diabetic retinopathy.
Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- The Effect of Periodontitis Severity on Diabetic Retinopathy: An Optical Coherence Tomography Study.Diagnostics (Basel, Switzerland) · 2026Article
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5 authors.
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Abstract
Purpose: Optical coherence tomography angiography was used to compare the changes of capillary density and thickness of the peripapillary retinal nerve fiber layer in patients with diabetes mellitus (DM) without diabetic retinopathy (DR) and patients with mild nonproliferative diabetic retinopathy (NPDR). Methods: In this prospective cross-sectional study, 62, 85, and 75 eyes of normal control group (NC), DM group, and NPDR group were included, respectively. All subjects received an optic-disc-centered 6 × 6-mm fundus scan. The annular region outside the optic disc boundary was divided into eight sectors: nasal superior, nasal inferior, inferior nasal (IN), inferior temporal (IT), temporal superior, temporal inferior, superior nasal, and superior temporal (ST). The average retinal nerve fiber layer thickness, average capillary density, and changes in thickness and capillary density of each sector in the annular region were calculated. Results: Compared with the NC group, the average capillary density of pRNFL in patients with DM and NPDR groups decreased significantly ( Conclusion: The pRNFL average capillary density in diabetic patients without DR and patients with mild NPDR, respectively, were significantly lower than that in healthy controls, especially in the NPDR group.
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