Evidence map›Paper›PMID 39926308›Full record

ArticleClinical epidemiology2025

Impact of Population-Based Screening for Diabetes and Prediabetes Among 67-Year-Olds Using Point-of-Care HbA1c on Healthcare Ultilisation, Results from the VISP Cohort.

Jesper Winkler Andersen, Annette Høgh, Jes Sanddal Lindholt, Rikke Søgaard, Henrik Støvring, Knud Bonnet Yderstræde, Annelli Sandbæk, Marie Dahl

Registry-linked trialAbstract read
In one paragraph

Article in Clinical epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03395509 (Intersectional Screening Program for Diabetes and Cardiovascular Diseases Among 67-years Old Citizens of the Municipal of Viborg), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03395509 enrolling by invitationnot on this map

Intersectional Screening Program for Diabetes and Cardiovascular Diseases Among 67-years Old Citizens of the Municipal of Viborg

TypeobservationalSponsorCentral Jutland Regional HospitalRan2014 to 2029Enrolled4,500ConditionsAging, Aortic Aneurysm, Abdominal, Hypertension, Mass Screening
3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesper Winkler AndersenVascular Research Unit, Department of Vascular Surgery, Viborg Regional Hospital, Viborg, Denmark.ORCID 0000-0003-2140-5464
Annette HøghVascular Research Unit, Department of Vascular Surgery, Viborg Regional Hospital, Viborg, Denmark.ORCID 0000-0001-7525-9007
Jes Sanddal LindholtVascular Research Unit, Department of Vascular Surgery, Viborg Regional Hospital, Viborg, Denmark.ORCID 0000-0001-9536-4488
Rikke SøgaardDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.ORCID 0000-0003-3557-8550
Henrik StøvringDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Knud Bonnet YderstrædeDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
Annelli SandbækDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Marie DahlVascular Research Unit, Department of Vascular Surgery, Viborg Regional Hospital, Viborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The present study aims to evaluate the changes in healthcare utilization following population-based screening for diabetes mellitus (DM) using point-of-care HbA1c measurement in the Viborg Screening Program (VISP) cohort, which invites all 67-year-olds in Viborg, Denmark, for cardiovascular disease (CVD) and DM screening. Patients and Methods: We conducted a cohort study using data from VISP and Danish national health registers. The study included 2386 individuals invited to VISP from August 1, 2014, to May 31, 2017. Exclusion criteria were non-attenders, those with prior DM, and those with missing HbA1c measurements. Pre- and post-screening healthcare utilization was analyzed, stratified by HbA1c levels: <42 mmol/mol (normal), 42-48 mmol/mol (pre-DM), and ≥48 mmol/mol (DM). Statistical analyses were performed using Poisson and logistic regression models to compare ratios of healthcare utilization before and after screening. Results: Of the participants, 16.5% had pre-DM, and 3.4% had DM. Screening resulted in increased general physician contacts across all HbA1c groups, the highest increase was seen in the DM group with a pre- vs post-screening odds ratio [OR] of 3.25 (95% CI: 1.06-9.95) and a relative odds ratio [ROR] of 2.70 (0.87-8.39). Also, in this group, the OR for having ≥1 HbA1c measurement one year pre- vs post-screening was 5.56 (2.77 -11.14) and 26.8% (17.6-37.9) started glucose-lowering treatment within two years post-screening. Despite expectations, healthcare utilization did not decrease among those with normal HbA1c levels. Conclusion: Population-based screening for DM and CVD among 67-year-olds resulted in increased healthcare utilization, particularly among those with screen-detected DM and pre-DM. The anticipated reduction in healthcare utilization among individuals with normal HbA1c levels was not observed. These findings highlight the potential for screening to enhance disease management and underscore the need for strategies to optimize healthcare resource use following screening, especially for individuals without DM. Trial Registration: NCT03395509.

Indexed as

Denmarkdiabetesepidemiologygeneral practicemedication

Identifiers

PMID39926308
PMCPMC11807345

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