ArticleRSC advances2025
Injectable carboxymethyl chitosan/oxidized dextran hydrogels containing zoledronic acid modified strontium hydroxyapatite nanoparticles.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Chitosan-quinoxaline Schiff base hydroxyapatite composite with antimicrobial properties for bone regeneration.Scientific reports · 2026Article
- Injectable hydrogels for bone regeneration: mechanical reinforcement strategies using nanoparticles and nanofibers.ADMET & DMPK · 2026Review
- Selenium Nanoparticles-Encapsulated Exosomes That Mitigate Acute Liver Injury via an Oral Carboxymethyl Chitosan/Oxidized Dextran Hydrogel.ACS applied materials & interfaces · 2025Article
- Emerging Role of Enzyme-Immobilized Nanocarriers in Osteoporosis: Advances and Challenges.International journal of nanomedicine · 2025Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanocomposite hydrogels have potential in bone regeneration due to the inorganic and polymeric material content. In this study, new types of nanocomposite hydrogels composed of zoledronic acid/strontium hydroxyapatite nanoparticles and carboxymethyl chitosan/oxidized dextran (CMC/OD) hydrogels were reported. Pure hydroxyapatite, 5%, 10% and 15% (w/w) strontium-substituted strontium hydroxyapatite nanoparticles were produced and then modified with zoledronic acid at ratios of 5% to 7.5% (w/w). These modified structures were then incorporated into CMC/OD hydrogels. Zoledronic acid modified strontium hydroxyapatite nanoparticles were characterized using Scanning Electron Microscopy (SEM), Energy Dispersive X-ray Spectroscopy (EDS) and X-ray Diffraction (XRD). CMC/OD structures were investigated using Fourier Transform Infrared Analysis (FTIR), Scanning Electron Microscopy (SEM). The physical properties of the hydrogels were determined
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Registered trials
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