Evidence map›Paper›PMID 39925971›Full record

ArticleFrontiers in nutrition2024

Fucoidan alleviated colitis aggravated by fiber deficiency through protecting the gut barrier, suppressing the MAPK/NF-κB pathway, and modulating gut microbiota and metabolites.

Weiyun Zheng, Shuangru Tang, Xiaomeng Ren, Shuang Song, Chunqing Ai

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weiyun ZhengSchool of Agronomy and Life Science, Shanxi Datong University, Datong, China.
Shuangru TangNational Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, China.
Xiaomeng RenNational Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, China.
Shuang SongNational Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, China.
Chunqing AiNational Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insufficient dietary fiber intake has become a global public health issue, affecting the development and management of various diseases, including intestinal diseases and obesity. This study showed that dietary fiber deficiency enhanced the susceptibility of mice to colitis, which could be attributed to the disruption of the gut barrier integrity, activation of the NF-κB pathway, and oxidative stress.

Indexed as

gut microbiotaIBD susceptibilityintestinal diseasesmetabolitespolysaccharide

Identifiers

PMID39925971
PMCPMC11802440

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.