Evidence map›Paper›PMID 39925944›Full record

ArticleSynthetic and systems biotechnology2025

Enhancing rufomycin production by CRISPR/Cas9-based genome editing and promoter engineering in

Chun Su, Nguyen-Quang Tuan, Wen-Hua Li, Jin-Hua Cheng, Ying-Yu Jin, Soon-Kwang Hong, Hyun Lee, Mallique Qader, Larry Klein, Gauri Shetye and 5 more

Abstract read
In one paragraph

Article in Synthetic and systems biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chun SuNational Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
Nguyen-Quang TuanDepartment of Bioscience and Bioinformatics, Myongji University, Yongin, Gyeonggi-Do, 17058, Republic of Korea.
Wen-Hua LiNational Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi'an, 710119, China.
Jin-Hua ChengMyongji Bioefficacy Research Center, Myongji University, Yongin, Gyeonggi-Do, 17058, Republic of Korea.
Ying-Yu JinR&D Center, Manbangbio Co. Ltd, Yongin, Gyeonggi-Do, 17058, Republic of Korea.
Soon-Kwang HongDepartment of Bioscience and Bioinformatics, Myongji University, Yongin, Gyeonggi-Do, 17058, Republic of Korea.
Hyun LeeInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Mallique QaderInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Larry KleinInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Gauri ShetyeInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Guido F PauliInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Scott G FlanzblauInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Sang-Hyun ChoInstitute for Tuberculosis Research, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Xin-Qing ZhaoState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Joo-Won SuhMyongji Bioefficacy Research Center, Myongji University, Yongin, Gyeonggi-Do, 17058, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-TuberculosisGenome miningPromoter engineeringRufomycinStreptomyces sp. MJM3502

Identifiers

PMID39925944
PMCPMC11803874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.