Development of a novelly selective HPLC-chemiluminescence method by targeting degradation intermediates of nitroimidazoles and its application in animal food products.

Mengdie Cai, Xinyu Wang, Kun Lu, Bixiao Zhou, Lijun Wei, Xianglei Cheng

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Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Mengdie CaiJiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330006, China.

Xinyu WangJiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330006, China.

Kun LuJiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330006, China.

Bixiao ZhouJiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330006, China.

Lijun WeiJiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330006, China.

Xianglei ChengJiangxi Province Key Laboratory of Preventive Medicine, School of Public Health, Nanchang University, Nanchang 330006, China.

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6 · The paper itself

Abstract

Residues of nitro-containing drugs in food and the environment have aroused social concern because of their excessive use for the treatment of human and animal diseases. The disadvantages of complex and time-consuming pretreatments in existing methods make it imperative to develop novel methods. Herein, with the aid of recognition probe MCLA, an excellent selective method for the detection of nitroimidazoles (NDZs) was developed based on high-performance liquid chromatography combined with ultraviolet (UV) degradation and chemiluminescence (HPLC-UV-CL). The study proposed an innovative process for the formation of SO

Indexed as

HPLC-Chemiluminescence detectionMechanismNitroimidazolesUV photolysis

Identifiers

PMID39925759

DOI10.1016/j.fochx.2025.102205

PMCPMC11803852

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.