Evidence map›Paper›PMID 39925710›Full record

ArticleBioactive materials2025

CD9-enriched extracellular vesicles from chemically reprogrammed basal progenitors of salivary glands mitigate salivary gland fibrosis.

Sunyoung Park, Yeo-Jun Yoon, Yongpyo Hong, Jianning Yu, Jae-Min Cho, Ye Jin Jeong, Haeun Yu, Hyorim Jeong, Hyunjin Lee, Seungyeon Hwang and 5 more

Abstract read
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sunyoung ParkSchool of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Yeo-Jun YoonDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Yongpyo HongDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Jianning YuSchool of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Jae-Min ChoDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Ye Jin JeongDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Haeun YuSchool of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Hyorim JeongThe DABOM Inc., 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Hyunjin LeeThe DABOM Inc., 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Seungyeon HwangDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Won-Gun KohDepartment of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Ji Yeong YangSchool of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Kyung-A HyunSchool of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Hyo-Il JungSchool of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seoul, 03722, Republic of Korea.
Jae-Yol LimDepartment of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) derived from stem cells offer promising potential for cell-free therapy. However, refining their cargo for precise disease targeting and delivery remains challenging. This study employed chemical reprogramming via dual inhibition of transforming growth factor beta (TGFβ) and bone morphogenetic protein (BMP) to expand salivary gland basal progenitor cells (sgBPCs). CD9-enriched (CD9

Indexed as

Extracellular vesicleFibrosisMicrofluidicsOrganoidRegenerationSalivary gland

Identifiers

PMID39925710
PMCPMC11803853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.