Evidence map›Paper›PMID 39925698›Full record

ArticleEJVES vascular forum2025

Association Between the Effectiveness and Magnitude of Foot Microcirculation Assessed by Radionuclide Angiography and One Year Limb Outcomes in Patients with Chronic Limb Threatening Ischaemia.

Takuya Hashimoto, Yoshitaka Kumakura, Kenichi Ichikawa, Satoshi Yamamoto, Takashi Endo, Masaya Sano, Osamu Sato, Juno Deguchi

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In one paragraph

Article in EJVES vascular forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takuya HashimotoDepartment of Vascular Surgery, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Yoshitaka KumakuraDepartment of Diagnostic Radiology and Nuclear Medicine, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Kenichi IchikawaDepartment of Diagnostic Radiology and Nuclear Medicine, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Satoshi YamamotoDepartment of Vascular Surgery, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Takashi EndoDepartment of Vascular Surgery, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Masaya SanoDepartment of Vascular Surgery, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Osamu SatoDepartment of Vascular Surgery, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.
Juno DeguchiDepartment of Vascular Surgery, Saitama Medical Centre, Saitama Medical University, Kawagoe, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Microcirculation focused evaluations may provide physiological insights that complement those of the established clinical criteria for patients with chronic limb threatening ischaemia (CLTI), since complex treatments are needed in this high risk population. However, current methods for quantitatively assessing foot microcirculation are limited. Thus, in this study, the aim was to demonstrate a proof of concept non-invasive method with novel parameters for assessing foot microcirculation. Methods: This was a single centre prospective cohort pilot study. The lower limbs of 13 patients diagnosed with CLTI were evaluated by radionuclide (RN) angiography with Results: The mean pedal transit time of the affected limbs in the non-healing group was longer than that in the healing group (19.1 ± 18.6 Conclusion: Two novel microcirculation parameters derived from RN angiography were associated with one year limb outcomes in patients with CLTI. Non-invasive radiotracer imaging derived parameters may provide an additional dimension to indices of pathophysiological microcirculation in CLTI.

Indexed as

Chronic limb threatening ischaemiaMicrocirculationPerfusion imagingPeripheral arterial diseaseRadionuclide angiographyTechnetium 99m tetrofosmin

Identifiers

PMID39925698
PMCPMC11803901

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