Evidence map›Paper›PMID 39925561›Full record

ArticleCureus2025

Prevalence of HPV Positivity and the Correlation Between P16INK4A Expression and HPV DNA Positivity in Carcinoma Oropharynx and Their Correlation With Survival Outcomes: A Retrospective Study From a Tertiary Cancer Centre in South India.

Amitha Sherief P, Lekha Madhavan Nair, Rejnish Ravikumar, Preethi Sara George, Kainickal Cessal Thommachan, Malu Rafi, Lakshmi S, Devasena Anantharaman, Radhakrishna Pillai M, Kunnambath Ramadas

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amitha Sherief PMedical Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
Lekha Madhavan NairRadiation Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
Rejnish RavikumarRadiation Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
Preethi Sara GeorgeEpidemiology and Biostatistics, Regional Cancer Centre, Thiruvananthapuram, IND.
Kainickal Cessal ThommachanRadiation Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
Malu RafiRadiation Oncology, Regional Cancer Centre, Thiruvananthapuram, IND.
Lakshmi SCancer Research, Regional Cancer Centre, Thiruvananthapuram, IND.
Devasena AnantharamanBiotechnology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, IND.
Radhakrishna Pillai MBiotechnology, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, IND.
Kunnambath RamadasRadiation Oncology, Clinical Operations and Allied Services, Karkinos Healthcare, Thiruvananthapuram, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been increasing worldwide. High-risk human papillomavirus (HPV) infection is now a well-recognised risk factor for oropharyngeal cancers. However, the information regarding the prevalence and outcome of HPV-related OPSCC is sparse in India. The study was conducted to identify the frequency of HPV infection in oropharyngeal cancer and also to study the treatment response and survival according to HPV positivity and p16

Indexed as

carcinoma oropharynxhpv dnahuman papillomavirusp16 ihcsurvival

Identifiers

PMID39925561
PMCPMC11806965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.