ArticleCureus2025
COVID-19 Humic/Fulvic Acid Plus Epigallocatechin Gallate Treatment: A Retrospective Chart Review.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe initial COVID-19 infection caused significant mortality in the nursing home setting. The mortality in our facility was approximately 50% and occurred in the later phase of the initial infection. In the nursing home setting, there were no approved treatment regimes. Specific treatment was left to the treating physician in concert with the administrative medical officials; immunizations were approved in December 2020. Concurrent publications indicated that epigallocatechin gallate (EGCG) and humic/fulvic acid with vitamin C possess the ability to interfere with the SARS-CoV-2 virus; both can inhibit viral attachment and reproduction, along with providing significant anti-inflammatory activity. They also exhibit good safety profiles and were previously utilized in our facility. With the high mortality and significant published data on inhibitory aspects of EGCG, humic/fulvic acid, and vitamin C, our facility utilized these supplements to treat COVID-19-positive patients.
methodsThis retrospective chart review analyzes the effectiveness of an integrative treatment consisting of EGCG and humic/fulvic acid with vitamin C provided to COVID-19 patients in a long-term care facility between October and December 2020. Nursing home patients with COVID-19 infections were either provided integrative treatment utilizing EGCG, humic/fulvic acid, and vitamin C or provided care without integrative support. All EGCG patients were informed, and, when needed, the first line of authority, power of attorney (POA) was contacted and informed that the integrative approach was not standard treatment (but was reviewed and approved by Pulaski Health and Rehabilitation Medical Facility directors and the patient's physician). Patients were informed of the safety literature and compounds' utilization in viral infections prior to accepting treatment.
resultsA review of 60 records indicates that among 22 patients receiving treatment with the integrative combination, there were no mortalities. Among 38 patients treated without this integrative support, there were 21 deaths. Conclusions: In a retrospective review of the treatment data, treatment of COVID-19 in the nursing home setting with EGCG, humic/fulvic acid, and vitamin C resulted in a significant reduction in overall mortality.
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