Evidence map›Paper›PMID 39925519›Full record

ArticleCureus2025

A Curious Case of Purple Chromaturia.

Richa Dhakal, George S Zacharia, Nismat Javed, Puja K C, Misbahuddin Khaja

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richa DhakalInternal Medicine, BronxCare Health System, Bronx, USA.
George S ZachariaInternal Medicine, BronxCare Health System, Bronx, USA.
Nismat JavedInternal Medicine, BronxCare Health System, Bronx, USA.
Puja K CInternal Medicine, BronxCare Health System, Bronx, USA.
Misbahuddin KhajaPulmonary Critical Care, BronxCare Health System, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxocobalamin, an antidote for cyanide toxicity, is known for its safety and efficacy. A notable side effect is dark red to purple chromaturia, sometimes mimicking hematuria. We report the case of a middle-aged female exposed to smoke inhalation following a house fire, who was treated on-site by emergency medical services with oxygenation and intravenous hydroxocobalamin and developed purple urine shortly after admission. Hematuria, hemolysis, rhabdomyolysis, and renal impairment were excluded with appropriate workup. The discoloration resolved spontaneously over five weeks without intervention, consistent with hydroxocobalamin-induced chromaturia. While benign and self-limiting, this phenomenon may cause diagnostic confusion and patient concern. Awareness of this side effect can prevent unnecessary investigations and reassure patients about its transient nature.

Indexed as

chromaturiacyanide toxicityhydroxocobalaminmanagementpurple urine

Identifiers

PMID39925519
PMCPMC11807389

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.