Evidence map›Paper›PMID 39925417›Full record

ArticleiScience2025

Virtual patients inspired by multiomics predict the efficacy of an anti-IFNα mAb in cutaneous lupus.

Vincent Hurez, Glenn Gauderat, Perrine Soret, Renee Myers, Krishnakant Dasika, Robert Sheehan, Christina Friedrich, Mike Reed, Laurence Laigle, Marta Alarcón Riquelme and 7 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Vincent HurezRosa and Co. LLC, San Carlos, CA, USA.
Glenn GauderatServier, Research and Development, Saclay, France.
Perrine SoretServier, Research and Development, Saclay, France.
Renee MyersRosa and Co. LLC, San Carlos, CA, USA.
Krishnakant DasikaRosa and Co. LLC, San Carlos, CA, USA.
Robert SheehanRosa and Co. LLC, San Carlos, CA, USA.
Christina FriedrichRosa and Co. LLC, San Carlos, CA, USA.
Mike ReedRosa and Co. LLC, San Carlos, CA, USA.
Laurence LaigleServier, Research and Development, Saclay, France.
Marta Alarcón RiquelmeGENYO Center for Genomics and Oncological Research, Granada, Spain.
Audrey AussyServier, Research and Development, Saclay, France.
Loubna ChadliServier, Research and Development, Saclay, France.
Sandra HubertServier, Research and Development, Saclay, France.
Emiko DesvauxServier, Research and Development, Saclay, France.
Sylvain FouliardServier, Research and Development, Saclay, France.
Philippe MoingeonServier, Research and Development, Saclay, France.
PRECISESADS Clinical Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lupus erythematosus is a heterogeneous autoimmune disease that requires treatments tailored to specific patient subsets. To evaluate

Indexed as

biological constraintscomputer simulationin silico biologymachine learningomics

Identifiers

PMID39925417
PMCPMC11804754

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.