Evidence map›Paper›PMID 39925203›Full record

ArticleAnalytical chemistry2025

Development of Receptor-Integrated Magnetically Labeled Liposomes for Investigating SARS-CoV-2 Fusion Interactions.

Tuhina Banerjee, Clayton Frazier, Neelima Koti, Paris Yates, Elizabeth Bowie, Megan Liermann, David Johnson, Sharon H Willis, Santimukul Santra

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tuhina BanerjeeDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.ORCID 0000-0001-6303-672X
Clayton FrazierDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.
Neelima KotiDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.
Paris YatesDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.
Elizabeth BowieDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.
Megan LiermannDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.
David JohnsonComputational Chemical Biology Core, University of Kansas, 2034 Becker Drive, Lawrence, Kansas 66018, United States of America.ORCID 0000-0003-4262-8173
Sharon H WillisIntegral Molecular Incorporation, One uCity Square 25 N. 38th Street, Suite 800, Philadelphia, Pennsylvania 19104, United States of America.
Santimukul SantraDepartment of Chemistry and Biochemistry, Missouri State University, 901 S. National Avenue, Springfield, Missouri 65897, United States of America.ORCID 0000-0002-5047-5245

Funding

Synthetic Chemical Biology CoreP20GM113117 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI OROZCO, ROBIN C. · 2016 to 2025
$23.9M
Investigation of Membrane Fusion Interactions of Enveloped Viruses using Magnetically-Labeled LiposomesR15GM146194 · NIGMS · PITTSBURG STATE UNIVERSITY · PI SANTRA, SANTIMUKUL · 2022 to 2022
$411k
NIGMS NIH HHS P20 GM113117NIGMS NIH HHS R15 GM146194
6 · The paper itself

Abstract

The impacts of highly pathogenic enveloped viruses, such as SARS-CoV-2, have turned scientific inquiry toward the fusion mechanisms responsible for viral pathogenesis and to seek cost-effective and adaptable strategies to mitigate future outbreaks. Current approaches for studying SARS-CoV-2 fusion include computational studies, pan-coronavirus viral inhibitors, and modified peptides and lipopeptides, along with various nanotechniques. Although these methodologies have illuminated the fusion mechanisms, they possess key limitations that prevent their widespread utility in outbreaks, including high financial or instrumental costs, operational proficiency, cytotoxicity, or viral specificity. This work measures changes in spin-spin T

Indexed as

LiposomesSARS-CoV-2Spike Glycoprotein, CoronavirusVirus InternalizationAngiotensin-Converting Enzyme 2COVID-19HumansACE2 protein, humanAngiotensin-Converting Enzyme 2LiposomesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID39925203
PMCPMC11883728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.