ArticleEuropean journal of neurology2025
From Tics to Stabs: Renaming Cluster Tics in Cluster Headache-A Cross-Sectional Study.
Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Primary stabbing headache in a tertiary headache centre.The journal of headache and pain · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShort-lasting paroxysms of facial pain in patients with cluster headache have traditionally been called "cluster tics." Mostly described as co-occurring trigeminal neuralgia, they remain to be explored as an independent phenomenon. We investigated the prevalence of cluster tics in cluster headache, the clinical differentiation from trigeminal neuralgia, and propose a distinct definition and renaming of cluster tics.
methodsWe conducted a retrospective, controlled, cross-sectional study using semi-structured interviews of patients with cluster headache at the Danish Headache Center. A comparator cohort of patients with trigeminal neuralgia was included from a previous study. We investigated the lifetime prevalence of cluster tics in the cluster headache group and characterized them according to duration, location, pain-intensity, triggerability, and serial occurrence.
resultsWe included 424 participants with cluster headache (median age 52 years (IQR: 32-72), male-female ratio 3:2) and 576 participants with trigeminal neuralgia (median age 72 years (IQR: 50-94), male-female ratio 1:3). Cluster tics were reported by 200 (47%) cluster headache participants with higher odds for participants of female sex (OR: 1.94, 95% CI: 1.27-2.96, p = 0.002) and participants with chronic cluster headache (OR: 1.74, 95% CI: 1.15-2.63, p = 0.008). Unlike trigeminal neuralgia, cluster tics were not triggerable (OR: 0.02, 95% CI: 0.01-0.04, p < 2e-16) and presented with pain restricted to the first trigeminal division.
conclusionsCluster tics are prevalent in nearly half of patients with cluster headache, associated to female sex and chronic phenotype. Unlike trigeminal neuralgia, cluster tics occur in the orbital region and are largely non-triggerable. To improve terminology, we propose renaming cluster tics to "cluster stabs."
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.