Evidence map›Paper›PMID 39924713›Full record

ArticleBrain tumor research and treatment2025

A Rare Case of Isolated Central Nervous System Neoplasm With Histiocytic Features.

Yoonsoo Choi, Yujin Lee, Young Il Kim, Seung Ho Yang

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain tumor research and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yoonsoo ChoiDepartment of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0009-0003-7346-368X
Yujin LeeDepartment of Hospital Pathology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-2840-6603
Young Il KimDepartment of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-6758-4344
Seung Ho YangDepartment of Neurosurgery, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. 72ysh@catholic.ac.kr.ORCID https://orcid.org/0000-0002-3490-1064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper discusses a rare case of a 49-year-old female diagnosed with a central nervous system-isolated neoplasm with histiocytic features, classified as histiocytic neoplasm, not otherwise specified (NOS). Despite comprehensive histopathological and genetic studies, accurately diagnosing the case proved challenging. Initial surgical findings and frozen biopsy suggested a low-grade glioma; however, subsequent immunohistochemistry and genetic analysis excluded known histiocytic subtypes such as ALK-positive histiocytosis and Erdheim-Chester disease. The patient's condition improved following occupational rehabilitation therapy for right upper motor weakness, as well as anticonvulsant and radiation therapy, and her neurological condition remains stable. This case underscores the diagnostic challenges of Histiocytic Neoplasms and the necessity for interdisciplinary collaboration and sophisticated diagnostic techniques.

Indexed as

Brain neoplasmsErdheim-Chester diseaseHistiocytosisImmunohistochemistry

Identifiers

PMID39924713
PMCPMC11813563

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