Evidence map›Paper›PMID 39924696›Full record

ArticlePhysiological reports2025

Antioxidant activity and protective effect of phyto-active compounds of Crataegus azarolus berries decoction extract against acetic acid-induced hepatorenal injuries in male rats.

Houcem Sammari, Anouar Abidi, Saber Jedidi, Nourhen Dhawefi, Hichem Sebai

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Houcem SammariLaboratory of Functional Physiology and Valorization of Bio-Resources, Department of Animal Physiology, University of Jendouba, Higher Institute of Biotechnology of Beja, Beja, Tunisia.ORCID https://orcid.org/0000-0003-0449-4098
Anouar AbidiLaboratory of Functional Physiology and Valorization of Bio-Resources, Department of Animal Physiology, University of Jendouba, Higher Institute of Biotechnology of Beja, Beja, Tunisia.ORCID https://orcid.org/0000-0002-4619-6892
Saber JedidiLaboratory of Functional Physiology and Valorization of Bio-Resources, Department of Animal Physiology, University of Jendouba, Higher Institute of Biotechnology of Beja, Beja, Tunisia.ORCID https://orcid.org/0000-0002-5405-8385
Nourhen DhawefiLaboratory of Functional Physiology and Valorization of Bio-Resources, Department of Animal Physiology, University of Jendouba, Higher Institute of Biotechnology of Beja, Beja, Tunisia.
Hichem SebaiLaboratory of Functional Physiology and Valorization of Bio-Resources, Department of Animal Physiology, University of Jendouba, Higher Institute of Biotechnology of Beja, Beja, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study evaluated the hepato-nephronal protective properties of Crataegus azarolus berries decoction extract (CAB-DE) on acetic acid (AA)-induced oxidative stress and metabolic disorders in rats. Animals (60 rats) were randomly divided into six groups (n = 10), with groups 1 and 2 being controls and groups 3, 4, and 5 given increasing doses of CAB-DE, group 6 were given gallic acid until ulcerative colitis was induced and then intoxicated by an acute intra-rectal infusion of AA. Our results showed that CAB-DE-oral administration had no signs of toxicity or abnormal behavior in rats, with a LD

Indexed as

AntioxidantsChemical and Drug Induced Liver InjuryCrataegusPlant ExtractsAcetic AcidAnimalsFruitKidneyLiverMaleOxidative StressRatsRats, WistarAcetic AcidAntioxidantsPlant Extractsacetic acidCrataegus azaroluskidneyliveroxidative stressrats

Identifiers

PMID39924696
PMCPMC11807846

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.