Evidence map›Paper›PMID 39924642›Full record

ReviewClinical and translational allergy2025

Expert opinion on gray areas in asthma management: A lesson from the innovative project "revolution in asthma" of the Italian thoracic society (AIPO-ITS).

Adriano Vaghi, Raffaele Antonelli Incalzi, Simona Barbaglia, Maria Beatrice Bilò, Francesco Bini, Mauro Carone, Lorenzo Cecchi, Alfredo Antonio Chetta, Andrea Claudio Comel, Fausto De Michele and 8 more

Abstract readReview
In one paragraph

Review in Clinical and translational allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Adriano VaghiFormer Head of Pneumology and Chief of the Department of Medicine and Rehabilitation, Guido Salvini Hospital-ASST Rhodense, Garbagnate Milanese (Milan), Italy.ORCID https://orcid.org/0009-0001-1896-2852
Raffaele Antonelli IncalziResearch Unit of Internal Medicine and Geriatrics, Department of Medicine and Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Simona BarbagliaPresident, National Patient Association Respiriamo Insieme-APS, Padova, Italy.
Maria Beatrice BilòDepartment of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy.
Francesco BiniRespiratory Unit, ASST Rhodense, Garbagnate Milanese (Milan), Italy.
Mauro CaroneDivision of Respiratory Disease and Respiratory Rehabilitation, Istituti Clinici Scientifici Maugeri, Pavia, IRCCS di Bari, Bari, Italy.
Lorenzo CecchiAllergy and Clinical Immunology Unit, San Giovanni di Dio Hospital, Florence, Italy.
Alfredo Antonio ChettaDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Andrea Claudio ComelPulmonology Unit, Pederzoli Hospital, Peschiera del Garda (Verona), Italy.
Fausto De MicheleRespiratory Unit, A. Cardarelli Hospital, Naples, Italy.
Giuseppe InsalacoItalian National Research Council (CNR), Institute of Translational Pharmacology (IFT), Palermo, Italy.
Antonino MusarraAllergy Unit, Casa della Salute di Scilla, Reggio Calabria, Italy.
Giovanni PomponioClinica Medica, Department of Internal Medicine, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy.
Antonio SpanevelloIstituti Clinici Scientifici Maugeri IRCCS, Pulmonary Rehabilitation Unit of Tradate Institute, Tradate (Varese), Italy.
Silvia TognellaRespiratory Unit, Mater Salutis Hospital, Legnago (Verona), Italy.
Alessandro VatrellaDepartment of Medicine Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.
Lina ZuccatostaInterventional Pulmonology Unit, A. Cardarelli Hospital, Naples, Italy.
Claudio MichelettoRespiratory Unit, Integrated University Hospital of Verona, Verona, Italy.

Funding

Menarini Group
6 · The paper itself

Abstract

backgroundDespite the availability of numerous guidelines for asthma management, their recommendations are not consistently implemented in clinical practice. This discrepancy between guidelines and real-world practice among Italian healthcare professionals was explored during the "Revolution in Asthma" training program, which identified "gray areas" and barriers preventing clinicians from adopting guideline-based approaches.

objectiveThis study aims to analyze the key challenges in asthma management and provide evidence-based solutions to improve adherence to guidelines in clinical practice.

methodsA group of experts from the Scientific Committee of the Revolution in Asthma project reviewed the program's findings, focusing on three main areas of asthma management: diagnosis, control, and treatment. The experts summarized clinicians' main needs and questions for each area and provided evidence-based responses and practical recommendations.

resultsThe study highlights critical challenges in asthma treatment, addressing two key questions: (a) What are the possible uses and indications for short-acting β-agonists in asthma patients? (b) How should asthma treatment be initiated and adjusted based on asthma control? The expert panel developed practical, operational tools to support general practitioners and specialists (pulmonologists and allergists) in optimizing asthma management.

conclusionThis paper serves as a knowledge co-creation initiative, bridging the gap between clinical guidelines and daily practice. By offering concrete recommendations, it aims to enhance the application of guideline-based asthma management among healthcare professionals.

Indexed as

asthmagray areasguidelinesreal‐lifetreatment

Identifiers

PMID39924642
PMCPMC11807766

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.