Evidence map›Paper›PMID 39924578›Full record

ArticleScientific reports2025

Comprehensive analysis of bacteriocins produced by clinical enterococcal isolates and their antibacterial activity against Enterococci including VRE.

Ayumi Fujii, Miki Kawada-Matsuo, Mi Nguyen-Tra Le, Yujin Suzuki, Saki Nishihama, Hideki Shiba, Tomonao Aikawa, Hitoshi Komatsuzawa

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Functional potential of gut microbiota inFrontiers in microbiology · 2026
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ayumi FujiiDepartment of Oral and Maxillofacial Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.
Miki Kawada-MatsuoDepartment of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi 1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan. mmatsuo@hiroshima-u.ac.jp.
Mi Nguyen-Tra LeDepartment of Oral and Maxillofacial Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.
Yujin SuzukiDepartment of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi 1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.
Saki NishihamaDepartment of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi 1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.
Hideki ShibaDepartment of Biological Endodontics, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.
Tomonao AikawaDepartment of Oral and Maxillofacial Surgery, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.
Hitoshi KomatsuzawaDepartment of Bacteriology, Hiroshima University Graduate School of Biomedical and Health Sciences, Kasumi 1-2-3, Hiroshima City, Hiroshima, 734-8551, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well-known that Enterococcus species produce bacteriocins that have antibacterial activity. However, a comprehensive analysis of the bacteriocin distribution among Enterococcus strains has not been conducted. In this study, we identified the bacteriocin genes from 80 Enterococcus faecalis and 38 Enterococcus faecium strains and investigated their antibacterial activity. In the 80 E. faecalis strains, the cytolysin gene (61.3%), enterolysin A gene (27.5%) and BacL

Indexed as

Anti-Bacterial AgentsBacteriocinsEnterococcus faecalisGram-Positive Bacterial InfectionsEnterococcus faeciumMicrobial Sensitivity TestsSpecies SpecificityVancomycin-Resistant EnterococciAnti-Bacterial AgentsBacteriocins

Identifiers

PMID39924578
PMCPMC11808071

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.